Patterns of gabapentin and pregabalin use and misuse: results of a population-based cohort study in France.

Patterns of gabapentin and pregabalin use and misuse: results of a population-based cohort study in France.

Publication date: Feb 08, 2019

The aim of this study was to assess the use and factors associated with misuse of gabapentin and pregabalin in the general French population, through a cohort study in the EGB (General Sample of Beneficiaries), a national representative sample of the French general population.

New users of gabapentin and pregabalin were identified from June 2006 to December 2014, and new users of duloxetine served as control group. Misuse was defined as a use of higher daily doses than recommended. Cox proportional hazard regression models were performed to identify associated factors of misuse.

Misuse was more frequent in the 8692 new users of pregabalin (12.8%), than in the 1963 gabapentin (6.6%) or the 3214 duloxetine new users (9.7%) (p

Driot, D., Jouanjus, E., Oustric, S., Dupouy, J., and Lapeyre-Mestre, M. Patterns of gabapentin and pregabalin use and misuse: results of a population-based cohort study in France. 17334. 2019 Br J Clin Pharmacol.



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