Increased level of plasma salusin-α and salusin-β in patients with multiple sclerosis.

Increased level of plasma salusin-α and salusin-β in patients with multiple sclerosis.

Publication date: Feb 05, 2019

Multiple Sclerosis (MS) is a potentially progressive autoimmune disorder of the central nervous system. The pathology of MS is characterized by inflammation, demyelination, reactive gliosis and neuronal damage. Salusin-α and salusin-β have been shown to be widely expressed in many tissues, including the central nervous system. In our study, we investigated whether salusin-α and salusin-β peptides had a relation with inflammation and whether it is related to Relapsing-Remitting Multiple Sclerosis (RRMS) disease.

Forty healthy controls and forty patients with RRMS were included in the study. Salusin-α and Salusin-β levels were measured by Enzyme-linked Immuno-Sorbent Assay (ELISA).

Salusin-α and salusin-β levels were high at a significant level in RRMS patients compared to healthy controls (p



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