Publication date: Mar 13, 2019
LabRoots – Drug Discovery Virtual Event 2019
Shivaani Kummar, MD, FACP – Professor of Medicine (Oncology) and of Radiology (Molecular Imaging Program at Stanford), Director Phase I Clinical Research, Director, Translational Oncology Program, Stanford University
Dr. Shivaani Kummar is a medical oncologist who specializes in early phase clinical drug development. She is Professor of Medicine and Director of the Phase I Clinical Research, Medical Oncology, and Translational Oncology Programs at Stanford University. She trained in Internal Medicine at Emory University in Atlanta, Georgia, and then pursued her fellowship training at the National Institutes of Health in Medical Oncology and Hematology. She then became Assistant Professor of Medicine at Yale Cancer Center, Yale University School of Medicine, where she developed in an interest in developmental therapeutics.
BASKET Trials: Biomarker Driven Drug Development
Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a given patient. In order to expeditiously evaluate a targeted agent against a potential ‘driver’ genetic aberration, so-called Basket trials are conducted. Basket trials enroll patients with multiple tumor types that carry a common genetic aberration and evaluate a single targeted treatment regimen. I will discuss the rationale, design, and challenges in conducting Basket trials.
1. Learn about when to consider conducting a Basket trial and how to design it
2. Learn about the promises and challenges of identifying patients based on genomic aberrations
Earn PACE/CME Credits:
1. Make sure you’re a registered member of LabRoots (https://www.labroots.com/virtual-event/drug-discovery-2019)
2. Watch the webinar on YouTube above or on the LabRoots Website (https://www.labroots.com/virtual-event/drug-discovery-2019)
3. Click Here to get your PACE (Expiration date – February 27, 2021 01:30 PM) – https://www.labroots.com/credit/pace-credits/3222/third-party
LabRoots on Social:
- Modeling systems from organoids to EHRs with Olivier Elemento | Talking Precision Medicine #07
- How is Precision Medicine Changing Cancer Care?
- Using GRAKN.AI to Represent Disease Networks – Conclusion (7/7)