The Beneficial and Debilitating Effects of Environmental and Microbial Toxins, Drugs, Organic Solvents and Heavy Metals on the Onset and Progression of Multiple Sclerosis.

The Beneficial and Debilitating Effects of Environmental and Microbial Toxins, Drugs, Organic Solvents and Heavy Metals on the Onset and Progression of Multiple Sclerosis.

Publication date: Mar 05, 2019

Multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system is common amongst young adults, leading to major personal and socioeconomic burdens. However, it is still considered complex and challenging to understand and treat, in spite of the efforts made to explain its etiopathology. Despite the discovery of many genetic and environmental factors that might be related to its etiology, no clear answer was found about the causes of the illness and neither about the detailed mechanism of these environmental triggers that make individuals susceptible to MS. In this review, we will attempt to explore the major contributors to MS autoimmunity including genetic, epigenetic and ecological factors with a particular focus on toxins, chemicals or drugs that may trigger, modify or prevent MS disease.

Hachim, M.Y., Elemam, N.M., and Maghazachi, A.A. The Beneficial and Debilitating Effects of Environmental and Microbial Toxins, Drugs, Organic Solvents and Heavy Metals on the Onset and Progression of Multiple Sclerosis. 17509. 2019 Toxins (Basel) (11):3.

Concepts Keywords
Autoimmunity Sjögren syndrome
Basel Microbial toxin
Central Nervous System Immunology
Epigenetic Autoimmunity
Etiology Epidemiology
Genetic Autoimmune diseases
Multiple Sclerosis Health
Socioeconomic Medical specialties
Medicine
Illness
Toxins chemicals drugs

Semantics

Type Source Name
disease MESH autoimmunity
disease DOID Multiple Sclerosis
disease MESH Multiple Sclerosis

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