Publication date: Apr 11, 2019
Now, Rutgers scientists have discovered that sensory signals in the brain’s cerebral cortex, which plays a key role in controlling movement and other functions, have a different pattern of connections between nerve cells and different effects on behavior than motor signals. The striatum, which integrates signals from the sensory and motor areas of the cerebral cortex, is severely compromised in diseases such as Parkinson’s and Huntington’s. “We found that stimulation of sensory cortex signals caused mice to stop their actions during a behavioral task, but motor cortex signals caused them to perform the task more impulsively,” said senior author David J. Margolis, an assistant professor in the Department of Cell Biology and Neuroscience in the School of Arts and Sciences at Rutgers-New Brunswick.
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