Chronic Postoperative Opioid Use: A Systematic Review.

Chronic Postoperative Opioid Use: A Systematic Review.

Publication date: May 09, 2019

There are a number of studies in the literature that describe the prevalence, causes, and factors associated with chronic postoperative opioid use, but there is a lack of synthesis of the literature to guide clinicians in optimally managing postoperative pain while avoiding opioid dependence. Thus, the goal of this study was to perform a systematic review of the literature to investigate the prevalence of chronic postoperative opioid use and the associated risk factors.

A systematic search was performed using Ovid Medline and Embase according to PRISMA guidelines. Data were collected on the following outcomes of interest: prevalence of opioid use at 3, 6, and 12 months postoperatively, and risk factors associated with chronic postoperative opioid use.

Forty-three articles were included in the final analysis. The mean prevalence of chronic postoperative opioid use in all populations at 3, 6, and 12 months postoperatively was 30.5%, 25.6%, and 25.2%, respectively. The prevalence of patients who developed chronic opioid use at 3, 6, and 12 months postoperatively was 10.4%, 8.5%, and 9.8%, respectively. Forty of the articles analyzed risk factors associated with chronic postoperative opioid use. The most common associated risk factor identified was preoperative opioid use with 27 articles demonstrating a significant association with chronic postoperative opioid use.

The current opioid crisis is in part secondary to the prevalence of chronic opioid use following surgery. This study identified associated risk factors with chronic postoperative opioid use, which may help identify patients at risk for developing chronic postoperative opioid use.

Hinther, A., Abdel-Rahman, O., Cheung, W.Y., Quan, M.L., and Dort, J.C. Chronic Postoperative Opioid Use: A Systematic Review. 03498. 2019 World J Surg.

Concepts Keywords
Embase Psychoactive drugs
Medline Perception
Opioid Pain
Opioid Dependence Substance dependence
Ovid Opioid use disorder
Pain Opioid receptors
Risk Factor RTT
Surgery
Chronic opioid 12months
Systematic search

Semantics

Type Source Name
disease MESH risk factors

Original Article

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