Scientists link ancient viruses to the chronic inflammation causing multiple sclerosis

Scientists link ancient viruses to the chronic inflammation causing multiple sclerosis

Publication date: May 11, 2019

Little is known about why the immune system turns on its own cells in autoimmune conditions, but scientists at Institut Pasteur say they have discovered a piece of the puzzle to what causes the inflammation associated with multiple sclerosis.

With MS, the central nervous system (brain, optic nerve, and spinal cord) become inflamed, damaging the myelin sheath, or the insulation and protective covering of the nerve cells.

Scientists at Institut Pasteur in Paris, France, report they’ve found that human endogenous retroviruses (HERVs) – also known as ancient viruses or fossil viruses – are involved in the central nervous system’s defensive response in multiple sclerosis.

Concepts Keywords
Autoimmune Autoimmune diseases
Brain Endogenous retrovirus
Central Nervous System Neurology
Christian Tumefactive multiple sclerosis
Demyelination Nervous systems
DNA MS
Endogenous Retroviruses MS inflammation
Epigenetic Organ systems
Facebook Multiple sclerosis
Fossil Branches of biology
France Nervous system
Immune System Neurological disorders
Inflammation Myelin
Institut Pasteur Demyelinating disease
Insulation
Memory
Multiple Sclerosis
Muscle Weakness
Myelin
Myelin Sheath
Nerve Cells
Nervous System
Optic Nerve
Paris
Puzzle
RSS Feed
Spinal Cord
Twitter
Viral
Virginia
Viruses

Semantics

Type Source Name
drug DRUGBANK Isoxaflutole
gene UNIPROT ZNF746
disease MESH demyelination
disease DOID multiple sclerosis
pathway BSID Immune System
disease MESH autoimmune disease
disease DOID autoimmune disease
disease MESH multiple sclerosis
disease MESH inflammation
disease DOID RSS
gene UNIPROT GRB10
gene UNIPROT SELENON
gene UNIPROT METTL8
gene UNIPROT TIPRL
gene UNIPROT ITFG1
gene UNIPROT KAT5

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