Clinical Correlations of Striatal Hand Deformities in Parkinson’s Disease.

Clinical Correlations of Striatal Hand Deformities in Parkinson’s Disease.

Publication date: May 14, 2019

Hand deformities have been recognized since the XIX century as part of the postural abnormalities observed in Parkinson’s disease (PD). However, their pathogenesis and clinical correlations are poorly understood.

We evaluated 104 hands of 52 consecutive patients with PD by high resolution photographs taken from the radial aspect of each hand; the degree of flexion of the 2 metacarpophalangeal (MCP) joint was measured by software. The presence of classical striatal hand deformity (CSHD) was also evaluated, defined as MCP flexion, proximal interphalangeal joint extension and distal interphalangeal joint flexion.

Patients with PD had a mean age of 63.3 +/- 12.7 years and 29 (56%) were males. The degree of MCP joint flexion in both hands showed moderate correlation with the MDS-UPDRS-III motor score (r=0.518, P

Baizabal-Carvallo, J.F., Alonso-Juarez, M., Murillo Ortiz, B., and Fekete, R. Clinical Correlations of Striatal Hand Deformities in Parkinson’s Disease. 20767. 2019 Acta Neurol Scand.

Concepts Keywords
Correlation Swan neck deformity
Distal Interphalangeal Joint Fingers
Flexion Metacarpophalangeal joint
Metacarpophalangeal Hand
Parkinson Medical classification
Pathogenesis Medical Subject Headings
Proximal Interphalangeal Joint Joints
Striatal Musculoskeletal system
Deformities
Software presence

Semantics

Type Source Name
disease MESH neurodegenerative disorders
gene UNIPROT ASXL1
gene UNIPROT PAFAH1B1
gene UNIPROT TET2
gene UNIPROT YWHAE
gene UNIPROT SF3B1
disease DOID MDS
gene UNIPROT CAPG
gene UNIPROT CD46
disease MESH abnormalities
disease MESH Hand Deformities

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