Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain

Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain

Publication date: May 22, 2019

The objective of this study is to evaluate the potential opioid-sparing effect associated with the novel combination of fentanyl and sub-dissociative ketamine in adult patients with moderate to severe pain in the emergency department.

Concepts Keywords
Abdominal Pain Respiratory depression
Adrenal Insufficiency Untreated cardiac arrest
Agonist Vomiting
Alcohol Vision nausea
Analgesia Laryngospasm
Analgesic Back pain
Anaphylaxis Hypertension hypotension dizziness
Anesthetic Open heart surgeries
Apnea Dialysis
Asthma Drugs
Attending Physician Opioids
Blood Pressure Psychoactive drugs
Blurred Vision RTT
Bpm Euphoriants
Bradycardia General anesthetics
Cardiac Arrest Morphinans
Chronic Pain Analgesics
Cirrhosis Ketamine
Clonic Fentanyl
Cocaine Morphine
Common Heroin
Department Dialysis
Depression
Dialysis
Diplopia
Dissociative
Dizziness
Drug Overdose
Elevated Blood Pressure
Fentanyl
Flank Pain
Heart Rate
Hydromorphone
Hypersensitivity
Hypertension
Hypotension
Intoxication
Ischemic Stroke
Ketamine
Laryngospasm
MmHg
Morphine
Musculoskeletal
Narcotics
Nausea
NMDA Receptor Antagonist
Nystagmus
Ohio
Opioid
Opioids
Orthopedic
Pain
Pain Medications
Pulmonary
Respiratory Depression
SDK
Sedation
Septic Shock
Serotonin Syndrome
Substance Abuse
United States
Vomiting

Semantics

Type Source Name
drug DRUGBANK Ketamine
drug DRUGBANK Fentanyl
disease MESH emergency
gene UNIPROT SPNS1
disease MESH chronic pain
disease MESH substance abuse
disease DOID substance abuse
drug DRUGBANK Ethanol
disease MESH narcotics
drug DRUGBANK Cocaine
disease MESH hypersensitivity
disease DOID hypersensitivity
disease MESH Depression
disease MESH Anxiety
disease DOID Anxiety
disease MESH Chronic obstructive pulmonary disease
disease DOID Chronic obstructive pulmonary disease
disease MESH Asthma
disease DOID Asthma
pathway BSID Asthma
disease MESH Cirrhosis
disease DOID Cirrhosis
gene UNIPROT SHBG
gene UNIPROT CCHCR1
disease MESH Ischemic heart disease
disease MESH Sepsis
disease MESH septic shock
gene UNIPROT NR4A2
gene UNIPROT ALG3

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