Multicenter study affirms benefit of Mohs micrographic surgery for melanoma

Multicenter study affirms benefit of Mohs micrographic surgery for melanoma

Publication date: Jun 01, 2019

In all noninvasive melanoma, 6-mm margins achieved histological tumor clearance in 77. 4% of tumors, 9-mm margins cleared in 92. 1% and 12-mm margins had complete clearance in 97. 1%.

To achieve 97% clearance, head/neck locations required a larger margin of 12 mm whereas 10 mm was needed in trunk/extremity locations (P

In recurrent noninvasive melanoma tumors, 6-mm margins met clearance in 48. 6%, 9 mm had 72. 9% clearance, 12 mm had 86. 4% and 21 mm reached 97. 3%.

The 34 recurrent head/neck noninvasive melanomas required 20 mm to achieve 97% clearance while the three trunk/extremity melanomas required 9 mm.

In recurrent invasive melanoma, 12-mm margins were needed for clearance in 45. 5% of tumors, 15 mm for 63. 6%, 18 mm for 72. 7%, 21 mm for 90. 9% and 30 mm for 100%.

Concepts Keywords
Eosin Basal-cell carcinoma
Hematoxylin Clinical medicine
Histological Cancer
Histologically Mohs surgery
Honolulu RTT
Melanoma Melanoma
Melanomas Medicine
Mohs Micrographic Surgery Cutaneous conditions
Mohs Surgery Neck tumors
Tumor Primary invasive melanoma
Head neck melanomas
Cost tumor
Preoperative tumor
Surgery
Skin cancer
Histological tumor
Recurrent invasive melanoma

Semantics

Type Source Name
gene UNIPROT RNMT
gene UNIPROT MET
gene UNIPROT SLTM
drug DRUGBANK Methionine
disease MESH tumor
gene UNIPROT MLANA
disease MESH tumor-free margins
pathway BSID Melanoma
disease DOID melanoma
disease MESH melanoma

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