Publication date: Jun 06, 2019
This led the Nobel Prize committee in 2018, to award Dr. James P. Allison the Nobel Prize. .. To treat melanoma, the most serious type of skin cancer, doctors have turned to surgery, chemotherapy, radiation therapy, and even immunotherapy, among other treatment options. 11, Pages 751: PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma Piperno-Neumann Roman-Roman NcE9mati Uveal melanoma (UM) remains without effective therapy at the metastatic stage, which is associated with BAP-1 (BRCA1 associated protein) mutations. Immune checkpoint inhibitors, alone or in combination with chemotherapy, as first-line treatment for advanced non-small cell lung cancer. The recent introduction of immune checkpoint inhibitors (ICI), has resulted in an increase in overall survival (OS) rates of patients with advanced NSCLC, as well as melanoma, urothelial carcinoma, renal cell carcinoma and head and neck carcinoma. 11, Pages 714: Targeting the Interplay between and the Immune System for Effective Immunotherapy Emily Roarty Jing Wang Fei Yang Michelle Barton Jeffrey Rosen Sendurai Mani Over the last decade, both early diagnosis and targeted therapy have improved the survival rates of many cancer patients. Most recently, immunotherapy has revolutionized the treatment options for cancers such as melanoma. Molecular characterization of non-responsive cancers suggest that an embryonic program known as epithelial-mesenchymal transition (EMT), which is .. . Evaluation of 18FFDG uptake after anti PD-1 therapy in mice Conclusion: This study is the first to assess early changes in [18F]FDG uptake by anti PD-1 treatment in a mouse B16F10 melanoma model.