Publication date: Jun 05, 2019
We aimed to investigate the values of midbrain area in diagnosing Parkinson’s Disease (PD) and progressive supranuclear palsy (PSP) by using transcranial sonography (TCS). Disease duration effect on brain sonographic findings could decrease the accuracy of TCS in PD and PSP patients. We reduced the disease duration effect on sonographic differences found between PD and PSP patients by using multivariate analysis.
Patients with clinical diagnosis of PSP and PD were recruited. We used SonoSite Edge II Ultrasound system to measure midbrain area, diameter of third ventricle and substantia nigra echogenicity. Diagnostic value of each measured area in sonography was estimated regarding its power for diagnosing PD or PSP. Independent sample t-test, Regression analysis and receiver operating characteristic (ROC) curve were performed using SPSS software.
Of 35 patients, 18 were PD and 17 PSP cases. The mean midbrain area was 4.86 +/- 0.71cm in PD patients and 3.61 +/- 0.85cm in those with PSP (P
Ghourchian, S., Mousavi, A., Zamani, B., Shahidi, G., and Rohani, M. Midbrain area for differentiating Parkinson’s disease from progressive supranuclear palsy. 21106. 2019 Clin Neurol Neurosurg (183):
|disease||DOID||progressive supranuclear palsy|
|disease||MESH||progressive supranuclear palsy|
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