Publication date: Jun 21, 2019
June 20, 2019 – Precision medicine could hold the key to more targeted, personalized care delivery, better outcomes, and diminished health disparities, but in order to turn these visions into reality, researchers have to study genetic mutations in diverse populations.
In one of the largest genetic studies of Hispanics and Latinos, African Americans, Asians, and other minorities, a team from Rutgers University examined genetic variants in nearly 50,000 people of non-European descent.
The findings revealed that a genetic mutation linked to blood sugar levels occurs in one percent of Hispanic/Latino people and about six percent of African Americans, but the mutation is rare in people of European descent.
Most genome-wide studies have been comprised of white people of European ancestry, the team said, but scientists have shown that the genetic mutations that contribute to chronic diseases may not be the same in all ethnicities.
-A genetic variant with a big effect in people of European descent may have a smaller effect in other populations, and vice versa. “
-The promise of precision medicine that improves health will not be achieved with studies based solely on people of primarily European ancestry,” said Tara Matise, a senior author and professor who chairs the Department of Genetics in the School of Arts and Sciences at Rutgers University – New Brunswick.
|drug||DRUGBANK||Dextrose unspecified form|
|disease||MESH||type 2 diabetes|