Gene-editing enzymes imaged in 3D

Gene-editing enzymes imaged in 3D

Publication date: Jul 09, 2019

July 8 (UPI) — Scientists have for the first time captured high-definition, 3D images of enzymes in the process of cutting DNA strands.

“These images provide us with invaluable information to improve the efficiency of the gene-editing process so that we can hopefully correct disease-causing DNA mutations more quickly and precisely in the future. “

“One of the main hurdles preventing the development of better gene-editing tools using Cas9 is that we didn’t have any images of it actually cutting DNA,” said University of Illinois researcher Miljan Simonovic, co-author of the new study.

Concepts Keywords
Anemia CRISPR gene editing
British Columbia Human Nature
Cancer Cas9
CRISPR Enzymes
Cryogenic Electron Microscopy Biotechnology
DNA Immune system
Enzyme Genetic engineering
Gene Genome editing
Gene Editing Life sciences
High Definition Branches of biology
Huntington Cut
Illinois Diseases
Nature Imaging
Scissors Precise version technology
Sickle Precise version technology
Tay Sachs Disease
The Breakthrough


Type Source Name
drug DRUGBANK Tropicamide
disease MESH cancer
disease DOID cancer
disease MESH sickle cell anemia
disease DOID sickle cell anemia
disease MESH Tay-Sachs disease
disease DOID Tay-Sachs disease
pathway BSID Release
disease MESH development


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