Cannabidiol-based Oral Treatment Seen to Promote Remyelination in Mice, Trial Planned in MS Patients

Cannabidiol-based Oral Treatment Seen to Promote Remyelination in Mice, Trial Planned in MS Patients

Publication date: Jul 09, 2019

This post was originally published on this siteEHP-101, a cannabidiol-based experimental therapy for multiple sclerosis, was able to recover myelin in damaged nerve fibers and lessen neuroinflammation in a mouse model of MS, data show. In two other MS mouse models – the experimental autoimmune encephalomyelitis (EAE) model, and Theiler’s murine encephalitis virus-induced (TMEV) – EHP-101 was also seen to prevent inflammation and myelin loss both in the spinal cord and brain. The post Cannabidiol-based Oral Treatment Seen to Promote Remyelination in Mice, Trial Planned in MS Patients appeared first on Multiple Sclerosis News Today. The post Cannabidiol-based Oral Treatment Seen to Promote Remyelination in Mice, Trial Planned in MS Patients appeared first on BioNewsFeeds.

Concepts Keywords
Australia Cannabidiol
Brain Multiple sclerosis
Cannabidiol Demyelinating disease
Cannabinoid Pharmacokinetics
Cannabis Cannabinoid
CB2 Experimental autoimmune encephalomyelitis
CBD Medical specialties
Central Nervous System Neurology
CEO Remyelination
Clinical Trials Organ systems
Controlled Substance Nervous system
Demyelination Inflammation demyelination
Drug Enforcement Administration Clinical systemic scleroderma
Encephalitis Experimental therapy
Hemp S activity demyelination
Holy Grail MS
Inflammation Inflammation
Marijuana Potential neuroprotective disease
Maryland Murine encephalitis virus
Molecule Cannabidiol products
Multiple Sclerosis Chemical entity
Murine
Myelin
Myelin Sheath
Nerve
Neuroprotective
Pharmacokinetics
PPAR Gamma
Psychotropic
Receptors
Spinal Cord
Systemic Scleroderma
Tolerability
VCE
Virus

Semantics

Type Source Name
drug DRUGBANK Nonoxynol-9
gene UNIPROT TNFSF13
disease DOID systemic scleroderma
gene UNIPROT ANP32B
disease MESH systemic scleroderma
pathway BSID Release
gene UNIPROT RNF128
gene UNIPROT MAGEE1
drug DRUGBANK Cannabidiol
gene UNIPROT SLC35G1
disease MESH multiple sclerosis
disease DOID multiple sclerosis
gene UNIPROT ARID1A
disease MESH inflammation
gene UNIPROT LAT2
drug DRUGBANK Medical Cannabis
gene UNIPROT CNR2
gene UNIPROT PPARA
disease MESH demyelination
disease MESH experimental autoimmune encephalomyelitis
disease MESH encephalitis
disease DOID encephalitis

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