Publication date: Jul 09, 2019

This post was originally published on this siteA new radiotracer called [F-18]PBR06, used in positron emission tomography (PET) imaging, helps detect changes in the brain’s grey matter that are linked to progressive forms of multiple sclerosis (MS), a study shows. The study, -Gray matter microglial activation in relapsing vs progressive MS: A [F-18]PBR06-PET study,” was published in the journal Neurology: Neuroimmunology & Neuroinflammation. However, disability progression in MS is linked with alterations in grey matter, specifically the activation of microglia – the central nervous system’s immune cells – and neuronal loss. In a Phase 1/2 study (NCT02649985), researchers determined whether a new molecule tracer, called [F-18]PBR06, could be used to measure activation of microglia in the grey matter of people with MS using PET. Results showed that, compared with the brains of healthy controls, activation of microglia in grey matter was higher in the MS patients. The post New PET Scan Radiotracer May Help Identify Early Signs of MS Progression, Study Reports appeared first on Multiple Sclerosis News Today.

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