Physical activity is associated with neuromuscular and physical function in patients with multiple sclerosis independent of disease severity.

Physical activity is associated with neuromuscular and physical function in patients with multiple sclerosis independent of disease severity.

Publication date: Jul 07, 2019

Purpose: Examine the association between physical activity and neuromuscular and physical function in patients with multiple sclerosis when also considering disease severity. Methods: 91 patients with multiple sclerosis were enrolled. Assessments included physical activity by 7-day thigh-worn accelerometry, knee extensor neuromuscular function by dynamometry (maximal isometric muscle strength, rate of force development (0-50 ms)), and physical function by 5cD7 sit-to-stand, 2-min walk test, and timed 25 ft walk test. Physical activity tertile comparisons along with simple and multiple regressions (adjusting for age, gender, EDSS, time since diagnosis) were performed. Results: Physical activity tertiles revealed differences (p 

Rooney, S., Riemenschneider, M., Dalgas, U., Jorgensen, M.K., Michelsen, A.S., Brond, J.C., and Hvid, L.G. Physical activity is associated with neuromuscular and physical function in patients with multiple sclerosis independent of disease severity. 18546. 2019 Disabil Rehabil.

Concepts Keywords
Accelerometry EDSS
Force
Gender
Isometric
Knee Extensor
Multiple Sclerosis
Muscle
Neuromuscular
Physical Activity
Tertile
Thigh

Semantics

Type Source Name
disease MESH diagnosis
disease MESH multiple
gene UNIPROT LITAF
gene UNIPROT SIT1
disease MESH development
disease DOID multiple sclerosis
disease MESH multiple sclerosis

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