Headache and Trigeminal Neuralgia in Multiple Sclerosis

Headache and Trigeminal Neuralgia in Multiple Sclerosis

Publication date: Aug 07, 2019

By far, the most common type of headache in patients with MS were migraines (39%), closely followed by medication overuse headaches (38%), and tension headaches (20%). 3 Although other studies demonstrated that more women with MS are likelier than men with MS to have migraines, the men in this study were slightly more likely than women to have migraines, at 40% and 38%, respectively. 3 Most of the patients with headache were treated with interferon beta (73. 8%), fingolimod (14. 8%), teriflunomide (7. 2%), and natalizumab (4. 3%). 3 -We believe that as a consequence of our methodology the headache prevalence reported in this paper reflects the frequency of headaches in MS patients more accurately,” wrote Dr Beckmann and Dr TcFCre.

“3 Pain is often a symptom of MS and TN is one of the most common pain syndromes associated with MS. 4 Patients with MS have a 20-fold chance of developing TN, regardless of the type of MS. 5 MRI is the usual diagnostic for MS and for TN secondary to MS. 5 Depending on the location of the nerve damage, MRI can help neurosurgeons identify the root cause of TN and can use the imaging for surgical microvascular decompression to treat the pain. 5 Often, TN precedes an MS diagnosis. 4 That was the premise behind a survey by neurologist Ahmad Fallata, MD, from the University of Manitoba, Winnipeg, Manitoba, Canada, and colleagues who queried 8590 patients in the North America Research Committee on Multiple Sclerosis Registry. 4 The prevalence of TN in this population was 9. 7%, with 15. 0% reporting that their facial pain preceded their MS diagnosis. 4 Patients most likely to report TN were women and those with longer TN duration and pain. 4 The mean age at TN presentation was 45. 3 years. 4 -TN can be primary (idiopathic) or secondary-that is due to some other underlying condition, such as a tumor or multiple sclerosis,” said coauthor and neurologist Ruth Ann Marrie, MD, PhD, FRCPC, associate professor from the University of Manitoba in Winnipeg, Canada in an interview with Neurology Advisor.

Concepts Keywords
Analgesia MRI
Canada Orofacial pain
Celebi Trigeminal neuralgia
Chronic Pain Neuralgia
Disability RTT
Fallata Migraine
Fingolimod Neurological disorders
FRCPC Organ systems
Frequency Pain
Glial Headaches
Headache Clinical medicine
Idiopathic Medicine
Interferon Pain Management
Interferon Beta Facial pain
Italy Medication overuse headaches
Izmir Disability sufferers headaches
Manitoba Women headaches
Migraine Pain
Migraines Tension headaches
Milan Another potential migraines
MRI Frequency headaches
Multiple Sclerosis Headaches
Natalizumab Tumor
Nerve Root imaging
Neurologist
Neurology
North America
Pain
Pharmacologic
Pharmacology
PhD
Physician
Prognosis
Survey
Symptom
Tension Headaches
Trigeminal Neuralgia
Tumor
Turkey
Winnipeg

Semantics

Type Source Name
disease MESH tumor
disease MESH diagnosis
gene UNIPROT MAGEE1
gene UNIPROT CYREN
gene UNIPROT IMPACT
drug DRUGBANK Natalizumab
disease MESH disease progression
disease MESH syndromes
gene UNIPROT PDC
gene UNIPROT CD69
gene UNIPROT DNMT1
disease MESH development
drug DRUGBANK Tropicamide
disease MESH medication overuse headaches
disease MESH tension headaches
gene UNIPROT IFNB1
drug DRUGBANK Fingolimod
drug DRUGBANK Teriflunomide
disease DOID Multiple Sclerosis
disease MESH Multiple Sclerosis
disease DOID Trigeminal Neuralgia
disease MESH Trigeminal Neuralgia
disease MESH chronic pain
disease DOID analgesia
disease DOID migraine
disease MESH men
disease DOID relapsing-remitting MS
disease MESH migraines

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