How Precision Medicine Could Boost Chronic Disease Management

How Precision Medicine Could Boost Chronic Disease Management

Publication date: Aug 09, 2019

Holding the potential for more targeted treatments, personalized care, and better patient outcomes, precision medicine has caught the attention of organizations across the care continuum, and researchers have increasingly demonstrated that it could revolutionize care delivery.

While precision medicine is frequently associated with and applied to cancer care, scientists have expanded their efforts to address other common chronic diseases with precision medicine and genomics methods.

What are some of the common chronic conditions that researchers are addressing with precision medicine strategies, and how can these strategies result in better patient care?

READ MORE: Studying Diverse Populations Will Strengthen Precision Medicine With these patients generating healthcare costs in the billions and trillions, there is a significant need to discover innovative methods of treatment for the disease.

READ MORE: Effective Precision Medicine Requires Moving Beyond the EHR -Such an approach may result in considerable health benefits by allowing more effective selection of individuals for treatments based on a priori known profiles of disease risk and their potential response to treatment. “

Targeting diabetes treatments READ MORE: NIH Clinical Trials Apply Genomics to Chronic Disease Management As a chronic disease that can affect almost every part of the body, diabetes is a condition that requires consistent, targeted care.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has made precision medicine for diabetes a priority with its Diabetes Genetics and Genomics program.

-The positive association between polygenic scores and type 2 diabetes we reported acknowledges the fact that people at higher genetic risk could benefit from additional strategies that have nothing to do with dietary fat intake,” said Jordi Merino, RD, PhD, of the MGH Diabetes Unit and Center for Genomic Medicine.

-This study adds to a growing body of evidence that different patients with mild asthma should be treated differently, perhaps using biomarkers like sputum eosinophils to select which drugs should be used-a precision medicine approach,” said James Kiley, PhD, director of the Division of Lung Diseases at NHLBI, In 2018, Mount Sinai Health System sought to put this idea into practice.

The institution partnered with Sanofi and Sema4 to launch a five-year, multisite study designed to advance precision medicine therapies for asthma patients.

Concepts Keywords
Asthma Prevalent chronic diseases
Biomarkers Future diabetes
Boston Genetic risk diabetes
Buffalo Treatments asthma
Chronic Diseases CareAlzheimers cognitive disorders
Cognitive High inflammatory cells
Concrete Spectrum diabetes
Dementia Common chronic diseases
Diabetes Precision therapies asthma
Digital Medicine
Eosinophils Health
Epigenetic Medical terminology
Fat Articles
Genetic RTT
Genetics Evidence-based medicine
Healthcare Diabetes management
Holistic Chronic condition
Immune System Preventive healthcare
Immunology Asthma
Inflammation Precision medicine
Intergenic Regions Neuroscience
Massachusetts General Hospital Mobile device
Merino Dementia
MGH Precision asthma
Mobile Device Part body diabetes
Mount Sinai Diabetes treatment
Nestle Concrete deployable solution
NIH Diabetes care
North America
Ona
PhD
Placebo
Polygenic
Polyunsaturated Fat
Precision Approach
Sanofi
Spectrum
Sputum
Steroids
Targeted Treatments

Semantics

Type Source Name
disease MESH Chronic Disease
drug DRUGBANK Tropicamide
disease MESH cancer
disease DOID cancer
disease MESH Aging
pathway BSID Aging
disease MESH dementia
disease DOID dementia
gene UNIPROT IMPACT
gene UNIPROT PTPN5
disease MESH risk factors
disease MESH Kidney Diseases
disease MESH type 2 diabetes
gene UNIPROT CD69
gene UNIPROT DNMT1
gene UNIPROT FAT1
gene UNIPROT CD36
gene UNIPROT PDC
disease MESH asthma
disease DOID asthma
pathway BSID Asthma
pathway BSID Immune System
disease MESH Allergy
disease DOID Allergy
disease MESH multi
disease MESH Lung Diseases
disease MESH Inflammation

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