New Wearable Device Helps Detect Dyskinesia in Parkinson’s

New Wearable Device Helps Detect Dyskinesia in Parkinson’s

Publication date: Aug 10, 2019

A new wearable device that assesses motor fluctuations may be a useful tool for detecting dyskinesia in patients with Parkinson’s disease, a new study suggests.

“The device, which is worn on the wrist like a watch, can tease out wearing off and dyskinesia and identify patients who need to see a neuro-specialist or who may need a neurosurgical procedure,” lead author, Echo E. Tan, MD, Cedars-Sinai Medical Center, Los Angeles, told Medscape Medical News.

“We found the device gave a more accurate assessment of symptoms than patient diaries, and the device was used more consistently than the diaries,” Tan added.

For the study, Tan and colleagues assessed 60 patients attending the Movement Disorders Clinic at Cedars-Sinai Medical Center with detailed questionnaires – Wearing Off Questionnaire (WOQ9) and Movement Disorders Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) Part IV scores – and assigned them into four disease categories: mild (no fluctuations); mild with minor fluctuations; moderate fluctuations, and severe bothersome fluctuations.

“We wanted to see if the device could distinguish between these different types of patients,” Tan said.

Results from the 54 subjects who completed the study showed that the fluctuation score on the device significantly differentiated between early fluctuators and troublesome fluctuators (P = .01), as well as dyskinetic and non-dyskinetic subjects (P

“We found that the device fluctuation score can distinguish between patients who do and do not have dyskinesia – ie the two milder groups and the two more severe groups.

“The fluctuator score appears to be a good triage tool – it can help physicians identify patients with these motor fluctuations without spending long periods of time at the clinic. “

Concepts Keywords
Bear Quantitative system device
Bradykinesia Wider deployment devices
Clinical Trials Fluctuation score device
Cognitive Impairment Wearable device
Dyskinesia Fluctuations levodopa dyskinesia
Europe Good cognitive impairment
Facebook High dyskinesia
Germany Bradykinesia
James Beck Disease
Levodopa Tremor bradykinesia dyskinesia
Los Angeles Graphical movement disorder
Medscape Neurological disorders
Movement Disorder Nervous system
Movement Disorders Medicine
Netherlands Health
Neurology RTT
Neurosurgical Syndromes
Parkinson Tardive dyskinesia
PhD Movement disorders
Sinai Tremor
Symptom Objective movement disorders
Tremor
Triage
Twitter
United Kingdom
Wearable Device
Wrist Watch

Semantics

Type Source Name
disease MESH Dyskinesia
drug DRUGBANK Levodopa
disease MESH movement disorders
disease MESH tremor
disease MESH bradykinesia
disease DOID MDS
gene UNIPROT PAFAH1B1
gene UNIPROT NR4A3
gene UNIPROT SIRPA
disease MESH cognitive impairment
gene UNIPROT DESI1
gene UNIPROT SLC35G1
gene UNIPROT PDC
disease MESH motor disorders

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