Publication date: Aug 10, 2019
A new wearable device that assesses motor fluctuations may be a useful tool for detecting dyskinesia in patients with Parkinson’s disease, a new study suggests.
“The device, which is worn on the wrist like a watch, can tease out wearing off and dyskinesia and identify patients who need to see a neuro-specialist or who may need a neurosurgical procedure,” lead author, Echo E. Tan, MD, Cedars-Sinai Medical Center, Los Angeles, told Medscape Medical News.
“We found the device gave a more accurate assessment of symptoms than patient diaries, and the device was used more consistently than the diaries,” Tan added.
For the study, Tan and colleagues assessed 60 patients attending the Movement Disorders Clinic at Cedars-Sinai Medical Center with detailed questionnaires – Wearing Off Questionnaire (WOQ9) and Movement Disorders Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) Part IV scores – and assigned them into four disease categories: mild (no fluctuations); mild with minor fluctuations; moderate fluctuations, and severe bothersome fluctuations.
“We wanted to see if the device could distinguish between these different types of patients,” Tan said.
Results from the 54 subjects who completed the study showed that the fluctuation score on the device significantly differentiated between early fluctuators and troublesome fluctuators (P = .01), as well as dyskinetic and non-dyskinetic subjects (P
“We found that the device fluctuation score can distinguish between patients who do and do not have dyskinesia – ie the two milder groups and the two more severe groups.
“The fluctuator score appears to be a good triage tool – it can help physicians identify patients with these motor fluctuations without spending long periods of time at the clinic. “