PlatformTM, a standards-based data custodianship platform for translational medicine research.

PlatformTM, a standards-based data custodianship platform for translational medicine research.

Publication date: Aug 13, 2019

Biomedical informatics has traditionally adopted a linear view of the informatics process (collect, store and analyse) in translational medicine (TM) studies; focusing primarily on the challenges in data integration and analysis. However, a data management challenge presents itself with the new lifecycle view of data emphasized by the recent calls for data re-use, long term data preservation, and data sharing. There is currently a lack of dedicated infrastructure focused on the ‘manageability’ of the data lifecycle in TM research between data collection and analysis. Current community efforts towards establishing a culture for open science prompt the creation of a data custodianship environment for management of TM data assets to support data reuse and reproducibility of research results. Here we present the development of a lifecycle-based methodology to create a metadata management framework based on community driven standards for standardisation, consolidation and integration of TM research data. Based on this framework, we also present the development of a new platform (PlatformTM) focused on managing the lifecycle for translational research data assets.

Open Access PDF

, Emam, , Elyasigomari, Matthews, A., Pavlidis, S., Rocca-Serra, P., Guitton, F., Verbeeck, D., Grainger, L., Borgogni, E., Del Giudice, G., Saqi, M., Houston, P., and Guo, Y. PlatformTM, a standards-based data custodianship platform for translational medicine research. 05181. 2019 Sci Data (6):1.

Concepts Keywords
Biomedical Informatics Articles
Informatics Lifecycle management
Lifecycle Analysis Translational research
Metadata Data management
Reproducibility Health informatics
Sci Knowledge
Information technology management
Metadata management

Semantics

Type Source Name
disease MESH development
disease MESH community

Similar

Original Article

Leave a Comment

Your email address will not be published. Required fields are marked *