Publication date: Sep 05, 2019
This post was originally published on this site A new gene editing method allows researchers to target many different kinds of disease-causing mutations in multiple cell types, which could have implications for genetic disorders such as Huntington’s disease, a study suggests. The new method was described in the journal Cell Research in a study, titled -Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction. ” In the new study, they expanded on HITI and developed SATI (intercellular linearized Single homology Arm donor mediated intron-Targeting Integration), which allows for more types of mutations to be edited. -We sought to create a versatile tool to target these non-coding regions of the DNA, which would not affect the function of the gene, and enable the targeting of a broad range of mutations and cell types,” one of the study’s co-authors, Mako Yamamoto, PhD, a postdoctoral fellow at the Salk Institute, said in a news release. The post New Gene-editing Tool SATI Can Target Different Kinds of Disease-causing Mutations, Mouse Study Suggests appeared first on Huntington’s Disease News. The post New Gene-editing Tool SATI Can Target Different Kinds of Disease-causing Mutations, Mouse Study Suggests appeared first on BioNewsFeeds.
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