How to stop MS in its tracks – Science Weekly podcast

How to stop MS in its tracks – Science Weekly podcast

Publication date: Sep 05, 2019

How to stop MS in its tracks – Science Weekly podcast Ian Sample visitsProfessor Richard Reynolds at theMS Society tissue bank to hear how research on brains of patients who died withmultiple sclerosis is leading to novel insights and new treatmentsContinue reading. .. Source: – Category: Science Authors: Presented by Ian Sample and produced by Max Sanderson and Iain Chambers Tags: Science Multiple sclerosis Society Neuroscience Parkinson’s disease Health Medicine Source Type: news Authors: Xiong H, Tuo QZ, Guo YJ, Lei P Abstract Iron has been proposed to be responsible for neuronal loss in several diseases of the central nervous system, including Alzheimer’s disease (AD), Parkinson’s disease (PD), stroke, Friedreich’s ataxia (FRDA), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS). The most common etiologies include acute changes due to (1) delirium or stroke, (2) movement disorders (Alzheimer dementia, Parkinson disease, multiple sclerosis, epilepsy), and (3) mood/behavior disorders (major depressive disorder, anxiety, bipolar disorder, schizophrenia). Among neurological diseases, epilepsy, dementia, Parkinson disea. .. Abstract Neurodegenerative diseases are progressive and uncontrolled gradual loss of motor neurons function or death of neuron cells in the central nervous system (CNS) and the mechanisms underlying their progressive nature remain elusive. There is urgent need to investigate therapeutic strategies and novel treatments for neural regeneration in disorders like Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS). Lloyd had forgotten the name of her grandma’s disease, hadn’t thought about it in .. . Purpose of review To review recent studies which assess comorbidity, that is, prevalence of co-occurrence, relationships and treatment implications between anxiety disorders and various medical illnesses. Recent findings The prevalence rates of anxiety disorders in patients with medical illnesses are high, with percentage up to 29% in patients with epilepsy, 48. 9% in patients with multiple sclerosis, 30. 1% in patients with Parkinson’s disease, 30% in patients with cardiovascular disease, 47. 0% in patients with diabetes mellitus, and so on. Abstract Chronic neurodegenerative and neuroinflammatory diseases, such as idiopathic Parkinson’s syndrome, amyotrophic lateral sclerosis and multiple sclerosis, represent a therapeutic challenge.

Concepts Keywords
Aging
Alcohol
ALS
Alzheimer
Amyotrophic Lateral Sclerosis
Anxiety
Anxiety Disorders
Arousal
Arthroplasty
Ataxia
Bipolar Disorder
Brain
Carbon
Cardiovascular Disease
Cellular Senescence
Central Nervous System
Chronic Diseases
Circadian Rhythms
Coffee
Comorbid
Comorbidity
Degenerative Diseases
Delirium
Dementia
Diabetes Mellitus
EDS
Epilepsy
Etiologies
Excessive Daytime Sleepiness
Exosomes
Fat
Fatigue
Fitness
Folate
Gene
Genetic
Homocysteine
Hospice
Huntington
Idiopathic
Intercellular Communication
Iron
Iron Overload
LncRNAs
Major Depressive Disorder
Metabolic Intermediate
Metabolism
Methionine
Motor Neurons
Movement Disorders
Multiple Sclerosis
Neural Regeneration
Neurodegenerative
Neurodegenerative Diseases
Neurological Diseases
Neuron
NKG2D
Nocturnal
Nucleic Acids
Nutrition
Oncogenic
Parkinson
Parkinson Disease
Pathogenesis
Pathophysiology
Patient Reported Outcomes
Phenotypic
Pluripotent
Podcast
Progressive
Proteinogenic Amino Acid
REM
Retinal
Schizophrenia
Sleep
Sleep Disorders
Smoking
SnCs
Somatic
Stroke
Sulfur
Surveillance
Swallow
Syndrome
Tumor
Tumor Suppressive
Vitamin

Semantics

Type Source Name
disease DOID major depressive disorder
disease MESH major depressive disorder
disease MESH behavior disorders
disease DOID epilepsy
disease MESH epilepsy
disease MESH delirium
disease MESH movement disorders
disease MESH Alzheimer dementia
disease MESH Parkinson disease
gene UNIPROT SERPINB1
drug DRUGBANK Guanosine
disease DOID Multiple sclerosis
disease MESH Multiple sclerosis
disease MESH sclerosis
gene UNIPROT MAX
gene UNIPROT MAP6
disease DOID Parkinson disease
disease MESH iron overload
gene UNIPROT IGFALS
disease DOID amyotrophic lateral sclerosis
gene UNIPROT FXN
disease MESH amyotrophic lateral sclerosis
disease MESH stroke
disease DOID stroke
drug DRUGBANK Iron
disease MESH anxiety
disease DOID anxiety
disease MESH bipolar disorder
disease DOID bipolar disorder
disease MESH schizophrenia
disease DOID schizophrenia
disease MESH sleepiness
gene UNIPROT IMPACT
disease MESH abnormalities
gene UNIPROT REM1
disease MESH sleep disorders
disease MESH dementia
disease DOID dementia
disease MESH Neurodegenerative diseases
pathway BSID Neurodegenerative Diseases
disease MESH death
disease MESH development
gene UNIPROT LARGE1
disease MESH tumor
pathway BSID Cellular Senescence
gene UNIPROT KLRK1
gene UNIPROT NR4A2
gene UNIPROT ALG3
disease MESH comorbidity
disease MESH anxiety disorders
disease MESH cardiovascular disease
disease MESH diabetes mellitus
disease DOID diabetes mellitus
disease MESH aging
pathway BSID Aging
disease MESH syndrome
disease DOID syndrome
drug DRUGBANK Albendazole
gene UNIPROT EHD1
disease MESH lifestyle
disease MESH habits
disease MESH chronic diseases
disease MESH hyperhomocysteinemia
disease DOID hyperhomocysteinemia
pathway BSID Carbon metabolism
drug DRUGBANK Methionine
disease MESH vitamin B deficiency
drug DRUGBANK Ethanol
gene UNIPROT FAT1
gene UNIPROT CD36
drug DRUGBANK Folic Acid

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