Mindful Body Awareness With Buprenorphine for Opioid Use Disorder Treatment

Mindful Body Awareness With Buprenorphine for Opioid Use Disorder Treatment

Publication date: Sep 09, 2019

The national opioid epidemic requires development of real-world evidence based treatments for opioid use disorder, including adjuncts to Medication Assisted Treatment (MAT) with buprenorphine. Interventions are needed that address the complex needs of patients with opioid use disorder, which include substantial mental health co-morbidity and high rates of chronic pain related to the complex interaction of opioid prescribing for pain and opioid use disorder. This study leverages recent federal and state opioid use disorder treatment initiatives as a platform for testing a promising mind-body intervention, Mindful Awareness in Body-oriented Therapy (MABT) as an adjunct to MAT in two clinical settings. MABT, a novel mindfulness-based intervention, uniquely addresses aspects of awareness, interoception, and regulation that may be associated with pain, mental health distress, and behavioral control that increase risk of relapse and poor treatment outcomes. Using a randomized, two-group, repeated measures design, we will compare those who receive MABT+ MAT to MAT only. The primary aim is to evaluate the effectiveness of MABT + MAT compared to MAT only in reducing opioid use and other substances. Assessments will be administered at baseline, post-intervention, and at 24 weeks follow-up.

Concepts Keywords
Adjuncts Opioid Disorder Treatment
Buprenorphine Treatments opioid disorder
Chronic Pain Pain opioid disorder
Cognitive Impairment Complex opioid disorder
Forego Federal opioid disorder
Gestation Mind body therapies
Interoception Massage
Massage Meditation
Mindfulness Opioids
Mindfulness Meditation RTT
Morbidity Morphinans
Opioid Drug rehabilitation
Opioid Epidemic Ethers
Pain Phenols
Psychosis Buprenorphine
Relapse Mindfulness
Washington Opioid use disorder

Semantics

Type Source Name
drug DRUGBANK Buprenorphine
disease MESH development
drug DRUGBANK Ilex paraguariensis leaf
gene UNIPROT ACAT1
disease MESH chronic pain
disease MESH relapse
gene UNIPROT CD69
gene UNIPROT DNMT1
gene UNIPROT DESI1
gene UNIPROT SLC35G1
pathway BSID Release
drug DRUGBANK Etoperidone
disease MESH psychosis
disease MESH cognitive impairment

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