Medication-Assisted Treatment for Opioid-Use Disorder.

Medication-Assisted Treatment for Opioid-Use Disorder.

Publication date: Oct 01, 2019

The United States is in the midst of a national opioid epidemic. Physicians are encouraged both to prevent and treat opioid-use disorders (OUDs). Although there are 3 Food and Drug Administration-approved medications to treat OUD (methadone, buprenorphine, and naltrexone) and there is ample evidence of their efficacy, they are not used as often as they should. We provide a brief review of the 3 primary medications used in the treatment of OUD. Using data from available medical literature, we synthesize existing knowledge and provide a framework for how to determine the optimal approach for outpatient management of OUD with medication-assisted treatments.

Oesterle, T.S., Thusius, N.J., Rummans, T.A., and Gold. Medication-Assisted Treatment for Opioid-Use Disorder. 04086. 2019 Mayo Clin Proc (94):10.

Concepts Keywords
Buprenorphine Opioids
Mayo RTT
Methadone Drug rehabilitation
Naltrexone Morphinans
Opioid Ethers
Opioid Epidemic Phenols
OUDs Buprenorphine
Opioid use disorder


Type Source Name
drug DRUGBANK Naltrexone
drug DRUGBANK Buprenorphine
drug DRUGBANK Methadone


Original Article

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