Georgetown Offering Clinical Trials To Study Lewy Body Dementia

Georgetown Offering Clinical Trials To Study Lewy Body Dementia

Publication date: Oct 09, 2019

Georgetown University Medical Center: Georgetown University Medical Center, a Lewy Body Dementia (LBD) Association Research Center of Excellence, is now offering three clinical trials to study new treatments for LBD, a disease often confused with Parkinson’s and Alzheimer’s disease.

With laboratory, biomarkers and clinical expertise in neurodegenerative diseases, including Lewy body dementia as well as Parkinson’s, Alzheimer’s and Huntington’s diseases, researchers at Georgetown are in a unique position to conduct translational research, identifying drugs that can be repurposed or new agents in the lab that can then be tested in patients.

The translational research is led by Charbel Moussa, MBBS, PhD, director of the Laboratory for Dementia and Parkinsonism, and scientific and clinical research director of the Translational Neurotherapeutics Program at Georgetown University Medical Center.

“The first clinical step in investigating drugs in Lewy body dementia is to carefully examine if the drug is safe and if it is tolerable,” says Pagan, principal investigator of the new studies and medical director for the Translational Neurotherapeutics Program.

Concepts Keywords
Alzheimer Parkinson’s disease
Biomarkers Parkinsonism
Brain RTT
Clinical Trials Organ systems
Cognitive Psychiatry
Dementia Lewy body dementia
Detective Psychiatric diagnosis
Dopamine Cognitive disorders
Georgetown Branches of biology
Hallucinations
Huntington
Leukemia
Lewy Body Dementia
MBBS
Movement Disorders
Neurodegenerative Diseases
Neurology
Nilotinib
Pagan
Parkinson
Parkinsonism
PhD
Principal Investigator
Tolerability
Tremor
Tyrosine Kinase

Semantics

Type Source Name
disease MESH Lewy Body Dementia
disease DOID Lewy Body Dementia
disease MESH tremor
disease MESH Movement Disorders
disease MESH hallucinations
disease MESH diagnosis
disease MESH neurodegenerative diseases
pathway BSID Neurodegenerative Diseases
gene UNIPROT LAT2
gene UNIPROT PDC
disease MESH Dementia
disease DOID Dementia
drug DRUGBANK Nilotinib
drug DRUGBANK Bosutinib
drug DRUGBANK L-Tyrosine
drug DRUGBANK Dopamine
disease MESH cancer
disease DOID cancer
disease MESH leukemia
disease DOID leukemia
gene UNIPROT PTPN5

Original Article

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