Society of Toxicologic Pathology Digital Pathology and Image Analysis Special Interest Group Article*: Opinion on the Application of Artificial Intelligence and Machine Learning to Digital Toxicologic Pathology.

Society of Toxicologic Pathology Digital Pathology and Image Analysis Special Interest Group Article*: Opinion on the Application of Artificial Intelligence and Machine Learning to Digital Toxicologic Pathology.

Publication date: Oct 23, 2019

Toxicologic pathology is transitioning from analog to digital methods. This transition seems inevitable due to a host of ongoing social and medical technological forces. Of these, artificial intelligence (AI) and in particular machine learning (ML) are globally disruptive, rapidly growing sectors of technology whose impact on the long-established field of histopathology is quickly being realized. The development of increasing numbers of algorithms, peering ever deeper into the histopathological space, has demonstrated to the scientific community that AI pathology platforms are now poised to truly impact the future of precision and personalized medicine. However, as with all great technological advances, there are implementation and adoption challenges. This review aims to define common and relevant AI and ML terminology, describe data generation and interpretation, outline current and potential future business cases, discuss validation and regulatory hurdles, and most importantly, propose how overcoming the challenges of this burgeoning technology may shape toxicologic pathology for years to come, enabling pathologists to contribute even more effectively to answering scientific questions and solving global health issues. [Box: see text].

Turner, O.C., Aeffner, F., Bangari, D.S., High, W., Knight, B., Forest, T., Cossic, B., Himmel, L.E., Rudmann, D.G., Bawa, B., Muthuswamy, A., Aina, O.H., Edmondson, E.F., Saravanan, C., Brown, D.L., Sing, T., and Sebastian, M.M. Society of Toxicologic Pathology Digital Pathology and Image Analysis Special Interest Group Article*: Opinion on the Application of Artificial Intelligence and Machine Learning to Digital Toxicologic Pathology. 05641. 2019 Toxicol Pathol.

Concepts Keywords
AI Neural networks
Analog Branches of biology
Artificial Intelligence Academic journals
Digital Medical specialties
Histopathological Anatomical pathology
Histopathology Toxicologic Pathology
Outline Digital pathology
Pathology Histopathology
Peering Artificial intelligence
Personalized Medicine
Scientific Community

Semantics

Type Source Name
gene UNIPROT RXFP2
disease MESH community
disease MESH development
gene UNIPROT IMPACT

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