Publication date: Nov 06, 2019
The researchers found cognitive decline shifted from worsening lesional pathology in stable relapsing-remitting MS (RRMS) to deep gray matter atrophy in converting RRMS and to accelerated cortical atrophy in progressive MS (PMS) only.
The Expanded Disability Status Scale was used to assess overall disability in patients with MS. There was no difference between patients with PMS and stable RRMS in terms of the annual rate of deep gray matter atrophy (-0. 82%/year vs -0. 71%/year, respectively; P =. 11).