Traffic Lights Intervention Reduces Therapeutic Inertia: A Randomized Controlled Trial in Multiple Sclerosis Care.

Traffic Lights Intervention Reduces Therapeutic Inertia: A Randomized Controlled Trial in Multiple Sclerosis Care.

Publication date: Feb 08, 2019

Background: Therapeutic inertia (TI) is a common phenomenon among physicians who care for patients with chronic conditions. We evaluated the efficacy of the traffic light system (TLS) educational intervention to reduce TI among neurologists with MS expertise. Methods: In this randomised, controlled trial, 90 neurologists who provide care to MS patients were randomly assigned to the TLS intervention (n = 45) or to the control group (n = 45). The educational intervention employed the TLS, a behavioral strategy that facilitates therapeutic choices by facilitating reflective decisions. The TLS consisted in a short, structured, single session intervention of 5-7 min duration. Participants made therapeutic choices of 10 simulated case-scenarios. The primary outcome was a reduction in TI based on a published TI score (case-scenarios in which a participant showed TI divided by the total number of scenarios where TI was possible ranging from 0 to 8). Results: All participants completed the study and were included in the primary analysis. TI was lower in the TLS group (1.47, 95% CI 1.32-1.61) compared to controls (1.93; 95% CI 1.79-2.08). The TLS group had a lower prevalence of TI compared to controls (0.67, 95% CI 0.62-0.71 vs. 0.82, 95% CI 0.78-0.86; p = 0.001). The multivariate analysis, adjusted for age, specialty, years of practice, and risk preference showed a 70% reduction in TI for the TLS intervention compared to controls (OR 0.30; 95% CI 0.10-0.89). Conclusions: In this randomized trial, the TLS strategy decreases the incidence of TI in MS care irrespective of age, expertise, years for training, and risk preference of participants, which would lead to better patient outcomes.

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Saposnik, G., Mamdani, M., Montalban, X., Terzaghi, M., Silva, B., Saladino, M.L., Tobler, P.N., and Caceres, F. Traffic Lights Intervention Reduces Therapeutic Inertia: A Randomized Controlled Trial in Multiple Sclerosis Care. 19414. 2019 MDM Policy Pract (4):1.

Concepts Keywords
Control Group Therapeutic inertia
Incidence Clinical trial
Multiple Sclerosis Randomized experiment
Multivariate Analysis Randomized controlled trial
Randomised Controlled Trial Knowledge
Randomized Trial Clinical research
TLS Health
Traffic Light Design of experiments
Chronic conditions
Disease
Multiple Sclerosis Care

Semantics

Type Source Name
disease MESH Multiple Sclerosis
disease DOID Multiple Sclerosis
gene UNIPROT TNFSF14
gene UNIPROT FUS
drug DRUGBANK Tropicamide

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