Publication date: Dec 01, 2019
To determine the influence of initial prescription size on opioid consumption after minor hand surgeries. Secondary outcomes include efficacy of pain control, patient satisfaction, and refill requests.
Retrospective studies have shown that opioid prescriptions for acute pain after surgical procedures are often excessive in size, which encourages misuse. This is the first prospective randomized trial on the influence of initial prescription size on opioid consumption in the setting of acute postsurgical pain.
In a prospective randomized trial at a single-academic institution, patients were provided an initial prescription of either 10 or 30?hydrocodone/acetaminophen (5/325?mg) pills after surgery. Two hundred opioid-naive patients, aged 19 to 69, undergoing elective outpatient minor hand surgeries were enrolled over 9 months, with a follow-up period of 10 to 14 days.
One hundred seventy-four patients were included in this analysis. Patients initially prescribed 30 pills (n = 79), when compared with patients initially prescribed 10 pills (n = 95), used significantly more opioid (P?=?
Gaddis, A., Dowlati, E., Apel, P.J., Bravo, C.J., Dancea, H.C., Hagan, H.J., Mierisch, C.M., Metzger, T.A., and Mierisch, C. Effect of Prescription Size on Opioid Use and Patient Satisfaction After Minor Hand Surgery: A Randomized Clinical Trial. 04281. 2019 Ann Surg (270):6.
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