Assessment of Deep Brain Stimulation Implantation Surgery: A Practical Scale.

Assessment of Deep Brain Stimulation Implantation Surgery: A Practical Scale.

Publication date: Nov 28, 2019

Deep brain stimulation (DBS) patients undergo extensive preoperative and postoperative evaluation, but the field lacks robust scoring system for quantifying DBS surgery.

To determine whether a practical scale could assess the DBS surgery and its clinical significance.

A retrospective study was performed of 150 patients undergoing DBS from February 2017 to February 2019. Independence analysis and multivariate testing was used to identify significant independent predictors. The scale scores were computed by summating across weighted predictors. Correlation between the scale scores and the intraoperative electrophysiological signal length (IESL), DBS power-on voltage, improvement rate in the Unified PD Rating Scale (UPDRS) and UPDRS III was analyzed and receiver operating characteristic (ROC) curve analysis quantified the discriminative capacity of the scale for predicting the prognosis.

List-wise exclusion of patients with incomplete datasets yielded a final sample of 130 Parkinson’s disease patients undergoing bilateral DBS. Multivariate testing identified 3 independent predictors of the prognosis including electrode implantation duration, postoperative pneumocephalus volume, and electrode fusion error. The scale scores were significantly correlated with the STN DBS power-on voltage (r=-0.4063, p

Gong, S., Tao, Y., Jin, H., Sun, X., Liu, Y., Wang, S., Xu, M., Yang, X., Wang, Y., Yuan, L., and Song, W. Assessment of Deep Brain Stimulation Implantation Surgery: A Practical Scale. 23148. 2019 World Neurosurg.

Concepts Keywords
DBS Parkinson’s disease
Deep Brain Stimulation Medical devices
Electrode Neurosurgical procedures
Electrophysiological Electrotherapy
Implantation Neurotechnology
Intraoperative Organ systems
Multivariate Testing Clinical medicine
Parkinson Medicine
Prognosis Surgery
Receiver Operating Characteristic Deep brain stimulation
ROC Curve Duration postoperative pneumocephalus
Voltage Deep brain stimulation
DBS
Pneumocephalus

Semantics

Type Source Name
disease MESH pneumocephalus
drug DRUGBANK Saquinavir

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