Publication date: Dec 02, 2019
The study, published in the journal Clinical Toxicology, looked at the effects of drugs called gabapentin and baclofen, both of which are used as opioid substitutes.
Suicidal thoughts are among the potential side effects of both drugs, and chronic pain itself is linked to suicide attempts.
Over the period the drugs were studied, suicides attempts after people took just gabapentin rose by 80. 5 percent, and by 43 percent for baclofen.
“We are seeing a worrying increase in harmful exposures to gabapentin and baclofen in U. S. adults over recent years, which may be an unintended consequence of the move away from opioid prescriptions for pain management,” said Reynolds.
“This research can build a better understanding of the risks so that providers and patients can make decisions regarding the role of these medications in their pain management based upon an evidence-informed risk-benefit analysis. “
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