Drugs Used to Replace Opioids Linked With Increase in Suicide Attempts Across U.S.

Drugs Used to Replace Opioids Linked With Increase in Suicide Attempts Across U.S.

Publication date: Dec 02, 2019

The study, published in the journal Clinical Toxicology, looked at the effects of drugs called gabapentin and baclofen, both of which are used as opioid substitutes.

Suicidal thoughts are among the potential side effects of both drugs, and chronic pain itself is linked to suicide attempts.

Over the period the drugs were studied, suicides attempts after people took just gabapentin rose by 80. 5 percent, and by 43 percent for baclofen.

“We are seeing a worrying increase in harmful exposures to gabapentin and baclofen in U. S. adults over recent years, which may be an unintended consequence of the move away from opioid prescriptions for pain management,” said Reynolds.

“This research can build a better understanding of the risks so that providers and patients can make decisions regarding the role of these medications in their pain management based upon an evidence-informed risk-benefit analysis. “

Concepts Keywords
Antispasmodic Baclofen
Baclofen Pain management
Central Nervous System Opioid
Chronic Pain Gabapentin
Drug Overdose Anxiolytics
Epidemic Anticonvulsants
Epileptic Morphine
Euphoria Chemical compounds
Fibromyalgia Calcium channel blockers
Gabapentin Psychoactive drugs
Healthcare RTT
Marijuana Pain management
Mental Illness Opioid epidemic doctors
Migraines Back pain
Muscle Relaxant Medications healthcare
Nerve Pain Medications pain management
Opioid Epidemic
Overdose Deaths
Pain Management
Respiratory Depression
Suicidal Thoughts
Unintended Consequence


Type Source Name
disease MESH Suicide
drug DRUGBANK Gabapentin
drug DRUGBANK Baclofen
disease MESH Chronic pain
disease MESH nerve pain
disease MESH migraines
disease MESH fibromyalgia
drug DRUGBANK Medical Cannabis
disease MESH spasms
disease MESH central nervous system disorders
disease MESH lower back pain
disease MESH respiratory depression
disease MESH seizures
drug DRUGBANK Tropicamide


Original Article

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