Parkinson’s drug can also curb dementia’s delusions, researchers find

Parkinson’s drug can also curb dementia’s delusions, researchers find

Publication date: Jan 07, 2020

A drug that curbs delusions in Parkinson’s patients did the same for people with Alzheimer’s disease and other forms of dementia, according to a study that was stopped early because the benefit seemed clear.

If regulators agree, the drug could become the first treatment specifically for dementia-related psychosis and the first new medicine for Alzheimer’s in nearly two decades.

-This would be a very important advance,” said one independent expert, Dr. Howard Fillit, chief science officer of the Alzheimer’s Drug Discovery Foundation.

He consults for Acadia and helped lead the study, which included about 400 people with dementia and psychosis.

Independent monitors stopped the study when they saw that those on dummy pills were more than twice as likely as those on the drug to relapse or worsen – 28% versus nearly 13%.

There were relatively few serious side effects – 5% in the drug group and 4% in the others.

Carrillo said the study was small, but the drug’s effect seemed large, and it’s not known whether the federal Food and Drug Administration would want more evidence to approve a new use.

Concepts Keywords
Acadia Hallucinations
Anxiety Pimavanserin
Brain Psychosis
Chicago Dementia
Cleveland Clinic Acadia Pharmaceuticals
Dementia Aging-associated diseases
Hallucinations Learning disabilities
Insurance Abnormal psychology
Las Vegas Cognitive disorders
Parkinson Medicine
Psychosis Psychiatric diagnosis
Psychotic Psychiatry
Relapse RTT
Ruvo Americans dementia
San Diego Drug curb dementia
Urinary Tract Infections Chemical
Cure dementia

Semantics

Type Source Name
disease MESH dementia
disease MESH delusions
disease MESH psychosis
disease MESH hallucinations
disease MESH anxiety
drug DRUGBANK Tropicamide
drug DRUGBANK Pimavanserin
disease MESH relapse
disease MESH urinary tract infections
disease MESH death

Original Article

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