Oxidative Balance in Opioid Therapy

Publication date: Jan 13, 2020

The oxidative – antioxidative balance is the crucial mechanism of opioid-induced immunomodulation. Additionally, impairement of cognitive function during opioid therapy is another important side- effect. This phenomenon was clearly described in opioids abuse. This is interesting to evaluate the importance of this subjects in chronic pain patients. The aim of the study was to investigate the oxidative – antioxidative homeostasis and cognitive functions using serum total oxidative capacity (TOC) and total antioxidative capacity (TAC) tests and Brain Derivered Neutrophic Factor (BDNF) in patient with chronic non-cancer pain treated with opioids.

Concepts Keywords
Anthropometric Back Pain
Antioxidative Chronic non cancer
BDNF Pharmacotherapy
Bialystok Pain
Cancer Pain Perception
Chronic Pain Branches of biology
Cognitive Nociception
Depression Morphine
Germany RTT
Homeostasis Opioids
Immunomodulation Brain-derived neurotrophic factor
Opioid Chronic pain
Opioids Cancer pain
Pharmacotherapy Low back pain
Poland Heroin


Type Source Name
drug DRUGBANK Isoxaflutole
disease MESH chronic pain
disease MESH cancer
disease MESH Back Pain
disease MESH depression


Original Article

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