Publication date: Feb 13, 2020
Now, thanks to the pooled data and insights from researchers around the world, USC researchers have the clearest picture yet of brain abnormalities associated with the serious mental illness that impacts 20 million people worldwide.
About a quarter of people with 22q develop schizophrenia or experience psychotic symptoms, so studying the syndrome provides a unique window into how such psychiatric problems develop over time.
To get a clear picture of the brain abnormalities associated with schizophrenia in individuals with 22q, the study’s authors examined magnetic resonance imaging (MRI) scans from 533 people with the disorder and 330 healthy control subjects.
Notably, the brain changes seen in people with 22q and psychosis significantly overlapped with the brain changes observed in previous neuroimaging studies of schizophrenia and other serious mental illnesses including bipolar disorder, major depression and obsessive-compulsive disorder.
|disease||MESH||22q11.2 deletion syndrome|