Sleep Disturbance Predicts Depression Symptoms in Early Adolescence: Initial Findings From the Adolescent Brain Cognitive Development Study.

Publication date: Feb 08, 2020

The aim of the study was to investigate associations between sleep disturbances and mental health in adolescents.

Data are from a national sample of 11,670 U.S. participants (5,594 females, aged 9-10 years, 63.5% white) in the Adolescent Brain Cognitive Development study. Initial longitudinal analyses were conducted for a subset of the sample (n = 4,951). Measures of youth sleep disturbance (disorders of initiating and maintaining sleep, sleep-wake transition disorders, and disorders of excessive somnolence) and “typical” total sleep time (number of hours slept on most nights in the past 6 months) were obtained from the parent-report Sleep Disturbance Scale (Data Release 2.0). Parent-report measures of youth mental health (depression, internalizing, and externalizing behaviors) from the Child Behavior Checklist and typical screen time were included.

At baseline, greater sleep disturbance and shorter total sleep time were associated with greater internalizing, externalizing, and depression scores. After controlling for baseline mental health symptoms, baseline sleep disturbance significantly predicted depression and internalizing and externalizing scores at 1-year follow-up. A significant interaction with sex indicated that the association between disorders of excessive somnolence and depression 1 year later was steeper for girls, compared with boys (p

Sleep disturbances predicted future mental health, particularly depression in this young sample, highlighting the potential to harness sleep as a tool to mitigate the persistence of depression across early adolescence and potentially prevent an adolescent onset of major depressive disorder.

Goldstone, A., Javitz, H.S., Claudatos, S.A., Buysse, D.J., Hasler, B.P., de Zambotti, M., Clark, D.B., Franzen, P.L., Prouty, D.E., Colrain, I.M., and Baker, F.C. Sleep Disturbance Predicts Depression Symptoms in Early Adolescence: Initial Findings From the Adolescent Brain Cognitive Development Study. 21014. 2020 J Adolesc Health.

Concepts Keywords
Adolescence Depression
Confidence Interval Persistence depression
Depression Neuroscience
Major Depressive Disorder Human behavior
Mental Health Psychiatry
Sleep Psychiatric diagnosis
Sleep Disturbance RTT
Sleep Disturbances Depression
Somnolence Sleep disorders
Externalizing disorders
Major depressive disorder
Internalizing disorder


Type Source Name
disease MESH Depression
disease MESH Development
disease MESH sleep
disease MESH disorders of initiating and maintaining sleep
disease MESH sleep-wake transition disorders
disease MESH disorders of excessive somnolence
pathway REACTOME Release
disease MESH major depressive disorder

Original Article

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