This common mental health drug may change the brain negatively

This common mental health drug may change the brain negatively

Publication date: Mar 02, 2020

In a new study, researchers found that a commonly used anti-psychotic medication was linked to adverse changes in brain structure.

But the adverse changes in brain structure found in this study are an important consideration for prescribing for psychiatric conditions where alternatives are possible.

The team found evidence that the use of olanzapine was linked to adverse changes in brain structure, namely a thinning of the cortex.

But participants who experienced a relapse of psychotic symptoms also had potentially adverse changes in brain structure, emphasizing the essential role antipsychotics play in treating disorders where psychosis is present.

Concepts Keywords
Antipsychotic MRI
Antipsychotics Magnetic Resonance Imaging
Anxiety Schizophrenia
Aristotle Psychosis
Autism Olanzapine
Brain Muscarinic antagonists
Brain Imaging Mood stabilizers
Cortex Psychopathology
Depression Atypical antipsychotics
Geriatric RTT
Gold Standard Drugs
Insomnia Psychiatry
Magnetic Resonance Imaging Serotonin antagonists
MRI Untreated illness
Olanzapine Remission
Pediatric Brain imaging techniques
Placebo Anxiety insomnia autism
Psychosis Pediatric geriatric disorders


Type Source Name
drug DRUGBANK Gold
disease MESH schizophrenia
disease MESH depression
disease MESH anxiety
disease MESH insomnia
disease MESH autism
disease MESH psychosis
drug DRUGBANK Olanzapine
drug DRUGBANK Sertraline
disease MESH relapse

Original Article

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