Does rTMS Induce Synaptic Plasticity?

Does rTMS Induce Synaptic Plasticity?

Publication date: Mar 17, 2020

The purpose of this study is to utilize the radioactive positron emission tomography (PET) tracer [11C]UCB-J to investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on synaptic plasticity. UCB-J has been validated as a marker for synaptic density (Finnema 2016, Nabulsi 2016). We will use this tracer to examine if rTMS leads to changes in synaptic plasticity, specifically changes in synaptic density, in individuals receiving rTMS for MDD (Holmes 2019, Chervyakov 2015). If rTMS is proven effective for increasing synaptic plasticity, there is a significant potential of a new applicable treatment for a variety of diseases that affect brain physiology.

Concepts Keywords
Body Habitus G claustrophobia
Brain Cochlear implants
Breastfeeding Branches of biology
Chronic Illness Neuroscience
Claustrophobia Nervous system
Cochlear Implants Neurophysiology
Contraindication Neural circuits
Ferromagnetic Neurology
Head Trauma Transcranial magnetic stimulation
MR Treatment of depression
Neurological Illness Plasticity
Organ Neuroplasticity
Pacemakers Synaptic plasticity
Palo Alto Tomography
PET
Physiology
Positron Emission Tomography
Psychosis
Radioactive
Resonance
RTMS
Sedation
Social Housing
Stanford
Synaptic
Synaptic Plasticity
Tracer
Unstable Angina

Semantics

Type Source Name
disease MESH Diagnosis
disease MESH Contraindication
disease MESH claustrophobia
disease MESH unstable angina
disease MESH psychosis
disease MESH Depressive Disorder

Original Article

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