Examination of associations between personality traits, and polymorphisms of MAO-A and 5-HTT with the severity of menopausal symptoms and depression levels.

Examination of associations between personality traits, and polymorphisms of MAO-A and 5-HTT with the severity of menopausal symptoms and depression levels.

Publication date: May 01, 2020

The aim of the present study was to investigate the association between different personality traits with monoamine oxidase A (MAO-A) and serotonin transporter (5-HTT), and to examine their effects on the severity of menopause symptoms as well as the levels of depression in menopausal women. The study was designed as an analytical cross-sectional study, performed on 132 healthy post-menopausal women in Iran. Personality was assessed using the Revised Edition of the NEO Personality Index (Neuroticism-Extroversion-Openness-Five Factor Inventory). The symptoms score sheet, used for measuring menopausal symptoms, was used to classify the participants according to their menopausal symptoms. Furthermore, Beck Depression Inventory short version was also used to assess depressive symptoms. Examination of blood samples taken from all participants was to identify DNA polymorphisms of 5-HTT using PCR. The results of the present study showed that a high level of neuroticism (P

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Concepts Keywords
Beck Depression Inventory Monoamine neurotransmitter
Blood Serotonin transporter
Cross Psychiatric diagnosis
Depression RTT
Extroversion Personality traits
Iran Amphetamine
Menopausal Psychology
Menopause Neuroscience
Monoamine Oxidase Branches of biology
Neuroticism Major depressive disorder
Openness Neuroticism
PCR Monoamine oxidase A
Polymorphisms
Serotonin Transporter

Semantics

Type Source Name
disease MESH depression
drug DRUGBANK Serotonin
disease MESH Neuroticism

Original Article

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