Potential Locations for Noninvasive Brain Stimulation in Treating Autism Spectrum Disorders-A Functional Connectivity Study.

Potential Locations for Noninvasive Brain Stimulation in Treating Autism Spectrum Disorders-A Functional Connectivity Study.

Publication date: Jan 24, 2020

Noninvasive brain stimulation (NIBS) is an emerging tool for treating autism spectrum disorder (ASD). Exploring new stimulation targets may improve the efficacy of NIBS for ASD.

We first conducted a meta-analysis on 170 functional magnetic resonance imaging studies to identify ASD-associated brain regions. We then performed resting state functional connectivity analysis on 70 individuals with ASD to investigate brain surface regions correlated with these ASD-associated regions and identify potential NIBS targets for ASD.

We found that the medial prefrontal cortex, angular gyrus, dorsal lateral prefrontal cortex, inferior frontal gyrus, superior parietal lobe, postcentral gyrus, precentral gyrus, middle temporal gyrus, superior temporal sulcus, lateral occipital cortex, and supplementary motor area/paracentral gyrus are potential locations for NIBS in ASD.

Our findings may shed light on the development of new NIBS targets for ASD.

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Concepts Keywords
Angular Gyrus Postcentral gyrus
Autism Spectrum Disorder Angular gyrus
Autism Spectrum Disorders Inferior frontal gyrus
Brain Autism spectrum
Dorsal Neuroanatomy
Functional Connectivity Gyrus
Gyrus Parietal lobe
Inferior Frontal Gyrus Cerebrum
Lateral Prefrontal Cortex Frontal lobe
Medial Prefrontal Cortex Gyri
Meta Analysis Brain
Occipital Cortex Precentral gyrus
Parietal Lobe Magnetic resonance imaging
Postcentral Gyrus
Prefrontal Cortex
Superior Temporal Sulcus
Supplementary Motor Area

Semantics

Type Source Name
disease MESH Autism Spectrum Disorders
disease MESH development

Original Article

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