Assessing the burden of COVID-19 in Canada

Assessing the burden of COVID-19 in Canada

Publication date: Jun 15, 2020

Background: The burden of COVID-19 in Canada is unequally distributed geographically, with the largest number of cases and fatalities recorded in Quebec and Ontario while other provinces experienced limited outbreaks. To date, however, no study has assessed how provincial epidemics have unfolded in a comparative perspective. This is essential to calibrate projections of the future course of the epidemic and plan health care resources for the second wave of infections. Methods: Using newly released individual-level data collected by the Public Health Agency of Canada, we assess COVID-19-related morbidity and mortality across age and gender groups at the provincial level through a combination of demographic and survival analyses. Results: Quebec has the highest absolute and per capita number of COVID-19 confirmed positive cases, hospitalizations and fatalities in all age groups. In each province, a higher number of women than men test positive for the disease, especially above age 80. Yet consistently across age groups, infected men are more likely to be hospitalized and enter intensive care than women do. These gender differences in hospitalisation rates account for the higher case fatality risk due to COVID-19 among men compared to women. Interpretation: Although health care capacity across provinces has been sufficient to treat severe cases, we find that the main factor accounting for gender differences in COVID-19-related mortality is the need for hospitalization and intensive care, especially above age 80. This suggests a selection effect of severe cases requiring to be treated in a hospital setting that needs to be further investigated.

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Concepts Keywords
Accounting Hospitalization rate oldest
Alberta Infections pharmaceutical interventions
Asymptomatic Positive infections
Atlantic Provinces Disease
Belgium Nationally COVID infections
British Columbia Public services diseases
Canada SARS
China Positive trajectory infection
CMAJ Care wave infections
Confidence Intervals Info diseases
Coronavirus Countries
Demographic International organizations
Epidemic World
Epidemiological RTT
Ethics Intensive care medicine
Europe Intensive care unit
Evolution Childbirth
France Canada
Gender Comorbidity
Globe Http
HEC Html
Hospital Pdf
Incidence
Infection
Intensive Care
Labrador
Magnitude
Morbidity
Mortality
Newfoundland
Northwest Territories
Nova Scotia
Nunavut
Nursing
Ontario
ONTARIO
Pandemic
Pathogen
Prairie Provinces
Prince Edward Island
Probability
Province
Quebec
REST
Spectrum
Spring Break
Standard Error
Stata
Statistics Canada
Sweden
Ventilator
Wuhan
Yukon

Semantics

Type Source Name
disease MESH infections
disease MESH men
disease MESH community
disease MESH death
disease MESH diagnosis
drug DRUGBANK Hyaluronic acid
drug DRUGBANK Etoperidone
disease MESH coronavirus infection
disease MESH Emerging Infectious Disease
disease MESH infectious disease

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