Impact of social distancing measures for preventing coronavirus disease 2019 : A systematic review and meta-analysis protocol

Impact of social distancing measures for preventing coronavirus disease 2019 : A systematic review and meta-analysis protocol

Publication date: Jun 15, 2020

Abstract Introduction: Social distancing measures (SDMs) protect public health from the outbreak of coronavirus disease 2019 (COVID-19). However, the impact of SDMs has been inconsistent and unclear. This study aims to assess the effects of SDMs (e.g. isolation, quarantine) for reducing the transmission of COVID-19. Methods and analysis: We will conduct a systematic review meta-analysis research of both randomised controlled trials and non-randomised controlled trials. We will search MEDLINE, EMBASE, Allied & Complementary Medicine, COVID-19 Research and WHO database on COVID-19 for primary studies assessing the enablers and barriers associated with SDMs, and will be reported in accordance with PRISMA statement. The PRISMA-P checklist will be used while preparing this protocol. We will use Joanna Briggs Institute guidelines (JBI Critical Appraisal Checklists) to assess the methodological qualities and synthesised performing thematic analysis. Two reviewers will independently screen the papers and extracted data. If sufficient data are available, the random-effects model for meta-analysis will be performed to measure the effect size of SDMs or the strengths of relationships. To assess the heterogeneity of effects, I2 together with the observed effects (Q-value, with degrees of freedom) will be used to provide the true effects in the analysis. Ethics and dissemination: Ethics approval and consent will not be required for this systematic review of the literature as it does not involve human participation. We will be able to disseminate the study findings using the following strategies: we will be publishing at least one paper in peer-reviewed journals, and an abstract will be presented at suitable national/international conferences or workshops. We will also share important information with public health authorities as well as with the World Health Organization.

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Concepts Keywords
Africa Search databases
African Americans Systematic meta protocol
Allied Pharmaceutical interventions
Anxiety Healthcare system
Asia Public involvement protocol
Asian Broader framework protocol
Australia Preparation protocol
Bedfordshire Sensitivity broad search
Black Caribbean Search interfaces
Boolean Operators Infections pharmaceutical interventions
China Mortality healthcare demand
Clinical Trials Pharmaceutical physical intervention
CMA Health
Cochrane Articles
Control Group Evidence-based practices
Coronavirus Systematic review
Cross Knowledge
Diabetes Meta-analysis
Dichotomous Critical appraisal
Dundee Social distancing
Eastern Mediterranean Randomized controlled trial
EMBASE Coronavirus
England Php
Epicentre Preparation protocol
Epidemic Broader framework protocol
Epidemiologic Html
Europe Pdf
Healthcare
Heterogeneity
Imperial College London
Infection Control
Inference
Influenza
Japan
Krishna
Luton
Mail
Mandalay
Manuscript
Mathematical Modelling
MEDLINE
Mendeley
MERS
MeSH
Meta Analysis
Michigan
Mixing
Mortality
Mortality Rate
Myanmar
North America
OR 22
Pandemic
Patient Isolation
PCR
Pharmaceutical
Pharmaceuticals
Physical Interventions
Protocol
Psychological Trauma
PubMed
Quarantine
Random Effects
Randomised Controlled Trials
Randomization
Randomized Controlled Trials
Renal
SARS
Sars
Sars Virus
SMD
Social Distance
Social Isolation
Socioeconomic Status
South East Asia
South Korea
Stress
Surveillance
Symmetry
Trim
Truncations
United Kingdom
Virus
Viruses
Western Pacific
Wuhan

Semantics

Type Source Name
drug DRUGBANK Coenzyme M
disease MESH infections
disease MESH renal
disease MESH separation
disease MESH influenza
disease MESH respiratory infections
disease MESH psychological trauma
disease MESH social distance
disease MESH anxiety
disease MESH depressions
disease MESH psychological distress
disease MESH coronavirus infections
disease MESH confusion
drug DRUGBANK Trimebutine
drug DRUGBANK Methionine
drug DRUGBANK Spinosad
disease MESH emergencies
drug DRUGBANK L-Phenylalanine

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