Mapping the Global Research and Clinical Trials in COVID-19

Mapping the Global Research and Clinical Trials in COVID-19

Publication date: Jun 28, 2020

COVID-19 has created an unprecedented level of research and innovation activity globally to bring out drug to control or cure the disease, and develop vaccine for long time prevention. A ‘new/better normal’ is emerging that is trying to push this time period for drug development and vaccine within a year and earlier than that from typical 8 to 10 years for drugs and 10 to 15 years for vaccine. This is happening due to multiple factors: strong policy push by different government that includes dedicated investment, speeding up regulation process, multiple agencies involvement, and multilateral bodies led by WHO trying to create a global platform, huge grants from private funding bodies, strategic linkages across the whole research and innovation value chain between firms, academic, research organisations and start-ups. The paper maps the research papers and ongoing clinical trials to provide an informed view of the current status of the research and drug development activity as seen through the lens of research papers and clinical trials. The intended goal of this study is to help the research community and policy makers to keep track of highly relevant research and drug development in COVID-19.


Concepts Keywords
Ai Chemoprophylaxis
Antibodies Antibody therapy
Antibody Treatment protocols
Antivirals Mechanical ventilation
Biomedical Ebola Marburg infections
Blood Epidemic stage
Body Treatment Substantial undocumented infection
Brazil High blood pressure
Bromley Infectious Diseases
California MERS diseases
Classifier Pneumonia
Clinical Trial Geographical locations influenza
Clinical Trials Illness
Coronavirus Hyper inflammation
CSIR Strain
Delhi Spread disease
Dispersion Treatment disease
Drug Development Control dangerous disease
Ebola Database search string
Economics Infectious Diseases Prevention
England Prior travel restrictions
Facebook Metal
Genetic Material Candidate vaccines Internet
Genome Internet San Diego
Germany Chest imaging size
Gilead Pharmaceutical sector
Hand Hygiene Social media tweets
Holbrook Blood products
India Virus Internet
Infection Viruses
Influenza Health
Intensive Care Unit Medicine
Interferon Beta 1a Zoonoses
Japan Coronaviridae
Lancet Animal virology
Lens Pneumonia
Logic Coronavirus
Marburg Betacoronavirus
MERS Remdesivir
Mortality Alpha
Mortality Rate Antibodies
Mulaney Care protocol
Nature Pdf
Nature Medicine Drug delivery
NIAID Drug Discovery
Pandemic Drug development
Santa Clara County
Viral Load
Viral Vector
Virus Shedding
Zhang Yang


Type Source Name
drug DRUGBANK Tropicamide
disease MESH development
disease MESH community
drug DRUGBANK Coenzyme M
drug DRUGBANK Lopinavir
drug DRUGBANK Ritonavir
drug DRUGBANK Interferon beta-1a
drug DRUGBANK Spinosad
disease MESH infections
disease MESH Allergy
disease MESH Infectious Diseases
disease MESH viral load
drug DRUGBANK Pentaerythritol tetranitrate
disease MESH Emerging Infectious Diseases
disease MESH Pneumonia
disease MESH Influenza
disease MESH virus shedding
disease MESH Critically Ill
disease MESH Acute Respiratory Distress Syndrome
disease MESH Rare Diseases
disease MESH Hospital Infection
drug DRUGBANK Ivermectin
drug DRUGBANK Copper
disease MESH Severe Acute Respiratory Syndrome
disease MESH Middle East Respiratory Syndrome
drug DRUGBANK Aluminium
drug DRUGBANK Silicon
drug DRUGBANK Ethanol
drug DRUGBANK Propyl alcohol
drug DRUGBANK Hydrogen peroxide
drug DRUGBANK Formaldehyde
drug DRUGBANK Povidone-iodine
disease MESH men
disease MESH hypertension
disease MESH cardiovascular disease
disease MESH complications
drug DRUGBANK Hydroxychloroquine
drug DRUGBANK Azithromycin
drug DRUGBANK Chloroquine
drug DRUGBANK Angiotensin II
drug DRUGBANK Medical air
drug DRUGBANK Losartan
disease MESH inflammation
drug DRUGBANK Tocilizumab
drug DRUGBANK Dexamethasone
drug DRUGBANK S-Arsonocysteine
drug DRUGBANK (S)-Des-Me-Ampa
disease MESH Arthritis

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