Emerging vaccine manufacturers are innovating for the next decade.

Publication date: Aug 07, 2020

The Developing Countries Vaccine Manufacturers Network (DCVMN) is a public health-driven alliance consisting of 43 vaccine manufacturers from 14 countries and territories, operating under the mandate to protect all people against known and emerging infectious diseases, by improving the availability of high-quality vaccines globally. The Network provides a platform for organizations to come together regularly to share technical information, best practices and future prospects. DCVMN members are playing an increasingly important role in public health supplying over 50% of the doses of vaccines procured by UNICEF globally. To evaluate the progress made by Network’s members, a survey consisting of 9 questions covering three important components of the manufacturers in the network was created, focusing on company dedicated human resources, vaccine production, and research and development efforts. Results show that more vaccines from more manufacturers are achieving WHO Pre-qualification, with areas of focus including the contributions to a Polio-free world, ending cholera, and tackling re-emerging diseases, such as measles. An increase by 50% of number of manufacturing companies holding WHO prequalified vaccines was observed from 2013 to 2019, strengthening open competitiveness for global vaccines supply. Notably, Network members have 181 vaccine projects in the research and development pipeline, highlighting novel vaccines against mosquito-borne diseases, such as dengue, chikungunya and Zika, novel human papillomavirus and pneumococcal conjugated vaccines. This report summarizes the progressive efforts of DCVMN members to contribute to reducing the burden of infectious diseases globally and details their commitment to vaccine innovation, particularly in the past five years, in the context of how vaccine innovations of today will shape the fight against infectious diseases tomorrow.

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Concepts Keywords
Chikungunya Medicine
Cholera Vaccination
Conjugated Vaccines Health
Dengue Medical specialties
Infectious Diseases Vaccination
Measles Diseases measles
Mosquito Cholera
Papillomavirus Contributions Polio
Pipeline Infectious diseases Polio
Pneumococcal Burden infectious diseases
Polio Vaccines manufacturers
Progressive Vaccine manufacturers
Public Health Important manufacturers network
Survey Vaccines
UNICEF Virology
Vaccine Polio eradication
Pentavalent vaccine
Vaccine-preventable diseases

Semantics

Type Source Name
drug DRUGBANK Nonoxynol-9
disease MESH infectious diseases
disease MESH dengue
pathway KEGG Measles
disease MESH measles
disease MESH cholera
disease MESH Polio
disease MESH development
disease MESH emerging infectious diseases

Original Article

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