Publication date: Aug 08, 2020
Discover a once-daily pill for people living with relapsing MS: ZEPOSIA(R) (ozanimod) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
ZEPOSIA is a once-daily pill Unlike many treatments for MS, ZEPOSIA is a pill that you take once a day.
FEWER RELAPSES In a one-year study, people who took ZEPOSIA had 48% fewer relapses than people who took a leading injectable medicine.
And in a two-year study, people who took ZEPOSIA had 38% fewer relapses than with a leading injectable.
† †In the one-year study, people taking ZEPOSIA had an Annualized Relapse Rate (ARR) of 0. 181 vs 0. 350 with a leading injectable.
MORE PEOPLE WERE RELAPSE FREE In the one-year study, 78% of people who took ZEPOSIA were relapse free at one year (versus 66% of people who took a leading injectable).
And in the two-year study, 76% of people who took ZEPOSIA were relapse free at two years (versus 64% of people who took a leading injectable).
FEWER NEW OR ENLARGING LESIONS (T2), TOO The one-year study also showed that people taking ZEPOSIA had 48% fewer new or enlarging lesions (T2) than people who took a leading injectable medicine.
And in the two-year study, people taking ZEPOSIA had 42% fewer new or enlarging lesions (T2) than with a leading injectable.
> >In the one-year study, people taking ZEPOSIA had an average of 1. 47 lesions (T2) vs 2. 84 with a leading injectable.
Possible serious side effects These are the serious side effects reported by people who took ZEPOSIA during the clinical studies.
Infections that can be life-threatening and cause death Slow heart rate when you start taking ZEPOSIA Liver problems Increased blood pressure Breathing problems, such as shortness of breath Macular edema (a vision problem) Swelling and narrowing of blood vessels in your brain Severe worsening of MS after stopping ZEPOSIA compared to before or during treatment Allergic reactions To learn more about these side effects and the possible symptoms, please see the Important Safety Information below.
Most common side effects During both of the clinical studies, people who took ZEPOSIA were asked to report any side effects that they experienced.
Call your healthcare provider right away if you have any of these symptoms of an infection during treatment with ZEPOSIA and for 3 months after your last dose of ZEPOSIA: fever feeling very tired flu-like symptoms cough painful and frequent urination (signs of a urinary tract infection) rash headache with fever, neck stiffness, sensitivity to light, nausea, or confusion (symptoms of meningitis, an infection of the lining around your brain and spine) Your healthcare provider may delay starting or may stop your ZEPOSIA treatment if you have an infection.
If you are a female who can become pregnant, talk to your healthcare provider about what birth control method is right for you during your treatment with ZEPOSIA and for 3 months after you stop taking ZEPOSIA are breastfeeding or plan to breastfeed.