Multiple Sclerosis & Vaccines including COVID-19

Multiple Sclerosis & Vaccines including COVID-19

Publication date: Jan 26, 2021

At this recording, the COVID-19 pandemic is raging with nearly 100 million people affected and over 2.1 million dead. Recently available COVID-19 vaccines are providing some much needed hope. Vaccinations have been extremely effective in saving people from fatal diseases but many people living with multiple sclerosis have questions about whether COVID-19 vaccines are safe and effective for them. This episode explains the two major COVID-19 vaccines types – mRNA and adenovirus – and what people with should know about them. This episode also covers different types of vaccines people with multiple sclerosis should avoid and which vaccines are safe. Experts tackle questions like whether vaccines can trigger MS relapses and review specific vaccines such as measles-mumps-rubella (MMR), chicken pox (varicella), hepatitis B and influenza (flu). Multiple sclerosis disease-modifying therapies (DMTs) can suppress the immune system and potentially impact whether a vaccine will be protective or not. Existing info on each MS medication type is discussed. Timing of vaccinations and medication dosing strategies covered. Vaccines as a strategy to prevent or treat multiple sclerosis are explored. Barry Singer MD, Director of The MS Center for Innovations in Care, interviews: Anne Cross MD is Professor of Neurology at Washington University in St. Louis and Dr. John Trotter MS Chair in Neuroimmunology. Her leading work in B cells in multiple sclerosis was recently recognized with the 2019 John Dystel Prize for MS Research. Amit Bar-or MD, FRCP is Professor of Neurology at University of Pennsylvania Perelman School of Medicine. He serves as Director of the Center for Neuroinflammation and Neurotherapeutics, and Chief of the Division of Multiple Sclerosis and Related Disorders. He runs a cellular and molecular neuroimmunology lab focused on injury and repair of the human central nervous system. Visit for more information. Share your MS story on

Concepts Keywords
Adenovirus Vaccinations
Antibodies Bypass
AstraZeneca Vaccination
Attenuated Vaccine Varicella
Attenuated Virus Infectious mononucleosis
Bacteria Sickness
Baptist SARS
Brain Upper respiratory infections
Central Nervous System Seasonal influenza
Chicken Pox Very serious disease
Chicken Pox Vaccine HBV infection
Chickenpox Coronavirus infections
Coronavirus Abnormal movements
Cove Cancers
DNA HIV infection
Epstein Barr Fatal diseases
Epstein Barr Virus Common viral infection
FRCP Zoster
Genetic Hypertensive, cardiovascular disease
Genetic Code Influenza
Hepatitis Mumps rubella
HIV Injury
Immune Memory Chicken pox virus
Immune Response Hepatitis B
Immune System Serious infections
Immunity Rabies
Immunologist Chicken pox
Immunology Measles
Infection Shingles
Infectious Mononucleosis Yellow fever
Influenza Chickenpox
Kobe HBV
Live Attenuated Vaccines Strokes
Marnie Certain disease
Measles Host cellular machinery
Memory Cellular machinery
Missouri Cell machinery
Molecule Medical specialties
Mono Medicine
Mount Drugs
MRNA Vaccines
Multiple Sclerosis Virology
Mumps Cancer vaccines
Muscle Medical research
Neurologist Influenza vaccine
Neurology Attenuated vaccine
Nucleus Vaccination
Okra COVID-19 vaccine
Oxford Antibodies
Pandemic Genetic code
Primary Care
Small Molecule
Spinal Cord
United States
Upper Respiratory Infections
Varicella Vaccine
Viral Infection
Viral Vector
Washington University
Yellow Fever


Type Source Name
disease MESH Multiple Sclerosis
disease MESH relapses
disease MESH measles
pathway KEGG Measles
disease MESH mumps
disease MESH rubella
disease MESH chicken pox
disease MESH hepatitis B
pathway KEGG Hepatitis B
disease MESH influenza
pathway REACTOME Immune System
drug DRUGBANK Tropicamide
disease MESH confusion
disease MESH cancers
disease MESH yellow fever
disease MESH zoster
disease MESH complications
drug DRUGBANK Isoxaflutole
disease MESH viral infection
disease MESH HIV infection
disease MESH infectious mononucleosis
disease MESH risk factors
disease MESH development
disease MESH infection
disease MESH diagnosis
drug DRUGBANK Hepatitis B Vaccine (Recombinant)
drug DRUGBANK Phosphate ion
drug DRUGBANK Varicella Zoster Vaccine (Live/Attenuated)
disease MESH upper respiratory infections
drug DRUGBANK Esomeprazole
drug DRUGBANK Acetate ion
disease MESH Rabies
disease MESH coronavirus infections
disease MESH cardiovascular disease
disease MESH community
disease MESH strokes
disease MESH abnormal movements
drug DRUGBANK Nonoxynol-9
drug DRUGBANK 7-Methyl-Gpppa

Original Article

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