Restoring dysfunctional lymphatic networks to allow the body to fight disease

Restoring dysfunctional lymphatic networks to allow the body to fight disease

Publication date: Apr 02, 2021

The human body is an incredibly designed machine, and mechanical processes such as those in the lymphatic system play major roles in maintaining healthy tissue and organs. He looks at how to restore dysfunctional lymphatic networks, which are associated with a wide range of diseases, including cancer, cardiovascular disease, diabetes, neurological conditions and metabolic syndromes. “Traditionally, medical students spent hours studying the cardiovascular system, but not as much emphasis was placed on the lymphatic system,” said Hanjaya-Putra. He studies the lymphatic system -; the part of the immune system that rids the body of toxins and other unwanted materials. Cells can sense mechanical stimuli, such as matrix stiffness, and this activates certain genes to promote lymphatic formation. “The reason, in large part, was due to the difficulty in visualizing lymphatic vessels, which are transparent. This type of research is only possible, Hanjaya-Putra said, because of advances in imaging and stem cell biology.

Concepts Keywords
Lymph sacs
Lymphangiogenesis
Endothelium
Lymphatic vessel
Angiology
Medical specialties
Branches of biology
Circulatory system
Lymphatic system
Disease diabetes
Wound cardiac injury
Dysfunctional lymphatic networks
Imaging

Semantics

Type Source Name
disease MESH cancer
pathway REACTOME Immune System
drug DRUGBANK Hyaluronic acid
disease MESH metabolic syndromes
disease MESH cardiovascular disease

Original Article

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