Plasma levels of nerve growth factor in Egyptian autistic children: Relation to hyperserotonemia and autoimmunity.

Plasma levels of nerve growth factor in Egyptian autistic children: Relation to hyperserotonemia and autoimmunity.

Publication date: Sep 15, 2021

Hyperserotonemia and brain-specific autoantibodies are detected in some autistic children. Nerve growth factor (NGF) stimulates the proliferation of B lymphocytes with production of antibodies and also increases mast cell serotonin release. This work was the first to investigate the relationship between plasma NGF and both hyperserotonemia and the frequency of serum anti-myelin basic protein (anti-MBP) auto-antibodies in 22 autistic children aged between 4 and 12 years and 22 healthy-matched controls. Levels of NGF, serotonin and anti-MBP were significantly higher in autistic children than healthy control children (P

Concepts Keywords
12years Branches of biology
Egyptian Growth factors
Healthy Developmental neuroscience
Hyperserotonemia Nerve growth factor
Serotonin Proteins
Myelin basic protein
Serotonin
Autoimmunity
NGF
Autoantibody
Antibodies

Semantics

Type Source Name
drug DRUGBANK Nerve Growth Factor
disease MESH autoimmunity
drug DRUGBANK Serotonin
disease MESH Autism

Original Article

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