Publication date: Jun 25, 2023
Objectives: Concerns among susceptible individuals, especially those with vascular malformations, have been raised by reports of thromboembolism following the administration of the SARS-CoV-2 vaccination against coronavirus disease 2019 (COVID-19). This study’s goal was to assess any negative side effects that patients with vascular malformations who received the SARS-CoV-2 vaccine reported after receiving it. Materials and Methods: Through the three patient groups for vascular malformations in Japan in November 2021, a questionnaire was distributed to patients with vascular malformations who were 12 years of age or older. Multiple regression analysis was used to find relevant variables. Results: A total of 128 patients responded, representing a response rate of 58. 8%. Ninety-six participants (75. 0%) had received at least one dose of SARS-CoV-2 vaccine. In total, 84 (87. 5%) and 84 (89. 4%) subjects experienced at least 1 general adverse response following dose 1 and dose 2, respectively. Adverse reactions related to vascular malformations were reported by 15 participants (16. 0%) after the 1st dose and 17 (17. 7%) after the 2nd dose. Notably, no case of thromboembolism following vaccination was reported. Conclusion: The rate of vaccine-related adverse reactions in patients with vascular malformations is not different from that reported in the general population. There is no report of life-threatening responses in the research population.
| Concepts | Keywords |
|---|---|
| Coronavirus | adverse reactions |
| Japan | COVID-19 |
| November | vaccination |
| Patient | vascular anomalies |
| vascular malformations |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | VO | vaccination |
| disease | MESH | Vascular Malformations |
| disease | VO | vaccine |
| disease | MESH | thromboembolism |
| disease | MESH | coronavirus disease 2019 |
| disease | VO | dose |
| disease | VO | population |
| disease | VO | report |
| disease | MESH | anomalies |