Many Chronic Pain Studies Omit Patients With Depression – HCPLive

Many Chronic Pain Studies Omit Patients With Depression – HCPLive

Publication date: Jun 27, 2023

The highest proportion of patients with depression were reported in RCTs evaluating fibromyalgia and mixed chronic pain (57. 1% and 61. 1%, respectively). RCTs including populations with mean scores at or above depression thresholds at baseline were categorized as including patients with depression. Chronic pain currently affects 20% of North American adults and is commonly associated with a variety of mental illness comorbidities, including depression. They also determined the variability of inclusion proportions based on gender, country, intervention type, pain type, and publication year. The lowest proportion of depression was observed in studies involving arthritis and axial pain (18. 6% and 26. 9%, respectively). Further, systemic biases regarding psychological conditions, as well as gender, may play an important in evaluating depression in fibromyalgia compared with other conditions like arthritis. Investigators identified 8 pain-type groups, such as fibromyalgia and axial pain, and 9 intervention types, including psychological, pharmacological, and exercise.

Concepts Keywords
Canada Chronic
Colleagues Depression
Depressive Depressive
Pharmacological Evaluating
Fibromyalgia
Gender
Including
Inclusion
Investigators
Pain
Proportions
Rcts
Significant
Symptoms
Trials

Semantics

Type Source Name
disease MESH Chronic Pain
disease MESH fibromyalgia
disease MESH arthritis
drug DRUGBANK Coenzyme M
disease MESH mental illness
disease MESH major depressive disorder

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