Publication date: Jun 27, 2023
The highest proportion of patients with depression were reported in RCTs evaluating fibromyalgia and mixed chronic pain (57. 1% and 61. 1%, respectively). RCTs including populations with mean scores at or above depression thresholds at baseline were categorized as including patients with depression. Chronic pain currently affects 20% of North American adults and is commonly associated with a variety of mental illness comorbidities, including depression. They also determined the variability of inclusion proportions based on gender, country, intervention type, pain type, and publication year. The lowest proportion of depression was observed in studies involving arthritis and axial pain (18. 6% and 26. 9%, respectively). Further, systemic biases regarding psychological conditions, as well as gender, may play an important in evaluating depression in fibromyalgia compared with other conditions like arthritis. Investigators identified 8 pain-type groups, such as fibromyalgia and axial pain, and 9 intervention types, including psychological, pharmacological, and exercise.
Semantics
Type | Source | Name |
---|---|---|
disease | MESH | Chronic Pain |
disease | MESH | fibromyalgia |
disease | MESH | arthritis |
drug | DRUGBANK | Coenzyme M |
disease | MESH | mental illness |
disease | MESH | major depressive disorder |